Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Neuroma embryonic sympathetic - Neuroblastoma. Review of the literature
Embryonic Neuroma sympathetic is derived from nerve cells, of which during normal development are sympathetic ganglia and the adrenal Medulla. Primary outbreak is found for this reason along the axis of the body - in the pelvis, retroperitoneal, bone ...
Agnieszka Budny +2 more
doaj +3 more sources
Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos [PDF]
We have used the vital dye, DiI, to analyze the contribution of sacral neural crest cells to the enteric nervous system in chick and mouse embryos. In order to label premigratory sacral neural crest cells selectively, DiI was injected into the lumen of ...
Bronner-Fraser, Marianne +3 more
core
Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu +12 more
wiley +1 more source
Age-dependent patterns of somatostatinergic neurons in sympathetic paravertebral ganglia
Aim. We aimed to determine the content of neurons expressing somatostatin (SST) and their colocalization with cells expressing tyrosine hydroxylase (TH) and neuropeptide Y (NPY) in the cranial cervical ganglion (CCG) and celiac plexus in rats ...
A. I. Emanuilov +3 more
doaj +1 more source
Developmental potential of trunk neural crest cells in the mouse [PDF]
The availability of naturally occurring and engineered mutations in mice which affect the neural crest makes the mouse embryo an important experimental system for studying neural crest cell differentiation.
Bronner-Fraser, Marianne +2 more
core
Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]
A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D +3 more
core +2 more sources
Unfused transverse foramen of the atlas vertebra in the Neandertal lineage fossils
Abstract In anatomically modern humans, the atlas can display an unfused transverse foramen (UTF) but currently the presence of UTF in the Neandertal lineage is uncertain due to a scarcity of prevalence studies and no exhaustive record of its presence throughout the entire hominin fossil record.
Asier Gómez‐Olivencia +5 more
wiley +1 more source
Optical Imaging of Pancreatic Innervation
At the time of Ivan Pavlov, pancreatic innervation was studied by looking at pancreas secretions in response to electrical stimulation of nerves.
Madina Makhmutova, Alejandro Caicedo
doaj +1 more source
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose +2 more
wiley +1 more source

