Results 21 to 30 of about 238,953 (314)

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

open access: yesNeurobiology of Disease, 2016
Rodent models of l-DOPA-induced dyskinesia (LID) are essential to investigate pathophysiological mechanisms and treatment options. Ratings of abnormal involuntary movements (AIMs) are used to capture both qualitative and quantitative features of ...
Irene Sebastianutto   +3 more
doaj   +1 more source

Basal ganglia calcification [PDF]

open access: yesBMJ Case Reports, 2013
A 65-year-old man presented to the emergency room after a fall, sustaining a head injury. A CT of the head showed diffuse, symmetric parenchymal calcifications involving the thalami globus palladi and caudate heads (figures 1 and 2). Detailed evaluation revealed a long-standing history of muscle cramps, involuntary choreiform movements and gradual ...
Rushad D, Patell   +3 more
openaire   +2 more sources

Dramatic differences in susceptibility to l-DOPA-induced dyskinesia between mice that are aged before or after a nigrostriatal dopamine lesion

open access: yesNeurobiology of Disease, 2016
Mice with striatal 6-hydroxydopamine (6-OHDA) lesions are widely used as a model to study the effects of neurorestorative, symptomatic, or antidyskinetic treatments for Parkinson's disease (PD).
Francesco Bez   +2 more
doaj   +1 more source

Neurotransmitters in the Basal Ganglia [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1984
ABSTRACTThe literature is reviewed on the afferents and efferents of the caudate/putamen, globus pallidus and substantia nigra, and on the neurotransmitters occurring in the various tracts. Emphasis is placed upon the diverse roles played by GABA and glutamate as transmitters in motor pathways and upon the probability that the substantia nigra pars ...
E G, McGeer, W A, Staines, P L, McGeer
openaire   +2 more sources

Significance of searching for ganglia in the terminal rectum/fistula of complex anorectal malformations: Related to defecation function

open access: yesFrontiers in Pediatrics, 2023
BackgroundThe need to search for ganglia in the terminal rectum/fistula of complex anorectal malformations (ARMs) remains controversial. This study aims to evaluate the relationship between ganglia absence in the terminal rectum/fistula and defecation ...
Wei Feng   +8 more
doaj   +1 more source

Neuropsychiatry of the basal ganglia [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2002
This review aims to relate recent findings describing the role and neural connectivity of the basal ganglia to the clinical neuropsychiatry of basal ganglia movement disorders and to the role of basal ganglia disturbances in "psychiatric"' states. Articles relating to the relevant topics were initially collected through MEDLINE and papers relating to ...
H A, Ring, J, Serra-Mestres
openaire   +2 more sources

Transcriptome analysis in a rat model of l-DOPA-induced dyskinesia

open access: yesNeurobiology of Disease, 2004
We have examined the pattern of striatal messenger RNA expression of over 8000 genes in a rat model of levodopa (l-DOPA)-induced dyskinesia and Parkinson disease (PD).
Christine Konradi   +7 more
doaj   +1 more source

Thoracic Part of Sympathetic Chain and its Branching Pattern Variations in South Indian Cadavers [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction: The sympathetic trunks are two ganglionated nerve trunks that extend the whole length of the vertebral column.The two trunks end by joining together to form a single ganglion, the ganglion impar.
Hemanth Kommuru   +4 more
doaj   +1 more source

Emotions and cognitive control: A comparison of bipolar disorder and schizophrenia

open access: yesJournal of Affective Disorders Reports, 2021
Background: Bipolar disorder (BP) and schizophrenia (SZ) are both psychiatric conditions characterized by deficits in cognitive control (executive function and attention) and emotion regulation. The emotional Stroop task makes it possible to measure such
Murielle Sollier-Guillery   +6 more
doaj   +1 more source

Subthalamic–pallidal interactions are critical in determining normal and abnormal functioning of the basal ganglia

open access: yes, 2002
The subthalamic nucleus (STN) and external globus pallidus (GP) form a recurrent excitatory–inhibitory interaction within the basal ganglia. Through a computational model of these interactions we show that, under the influence of appropriate external ...
Willshaw, D.   +3 more
core   +1 more source

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