Results 31 to 40 of about 238,953 (314)

Persistence of a T Cell Infiltrate in Human Ganglia Years After Herpes Zoster and During Post-herpetic Neuralgia

Frontiers in Microbiology, 2019
Varicella-zoster virus (VZV) is a human herpesvirus which causes varicella (chicken pox) during primary infection, establishes latency in sensory ganglia, and can reactivate from this site to cause herpes zoster (HZ) (shingles).
Jeremy P. Sutherland, Megan Steain, Michael E. Buckland, Michael Rodriguez, Anthony L. Cunningham, Barry Slobedman, Allison Abendroth   +6 more
doaj   +1 more source

Distribution of Molecules Related to Neurotransmission in the Nervous System of the Mussel Crenomytilus grayanus

Frontiers in Neuroanatomy, 2020
In bivalves neurotransmitters are involved in a variety of behaviors, but their diversity and distribution in the nervous system of these organisms remains somewhat unclear.
Elena Kotsyuba, Alexander Kalachev, Polina Kameneva, Vyacheslav Dyachuk, Vyacheslav Dyachuk   +4 more
doaj   +1 more source

The gross anatomy of the nervous system of Bothriurus bonariensis (L. C. KOCH, 1842) (Scorpiones, Bothriuridae) [PDF]

Brazilian Journal of Biology, 2002
The nervous system of the order Scorpiones appears to have a common organizational structure. The combination of an anatomical study using methylene blue as the contrast medium together with a histological analysis using hematoxylin-eosin and Heindenhain´
A. C. M. HORN, M. ACHAVAL
doaj   +1 more source

APOE ε4 allele, along with G206D-PSEN1 mutation, alters mitochondrial networks and their degradation in Alzheimer’s disease

Frontiers in Aging Neuroscience, 2023
IntroductionAlzheimer’s disease remains the most common neurodegenerative disorder, depicted mainly by memory loss and the presence in the brain of senile plaques and neurofibrillary tangles.
Irene Costa-Laparra, Elena Juárez-Escoto, Elena Juárez-Escoto, Carlos Vicario, Carlos Vicario, Rosario Moratalla, Rosario Moratalla, Patricia García-Sanz, Patricia García-Sanz   +8 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease

Neurobiology of Disease, 2011
6-Hydroxydopamine (6-OHDA) lesions are being used in the mouse for basic research on Parkinson's disease and L-DOPA-induced dyskinesia. We set out to compare unilateral lesion models produced by intrastriatal or intramesencephalic injections of a fixed 6-
Veronica Francardo, Alessandra Recchia, Nataljia Popovic, Daniel Andersson, Hans Nissbrandt, M. Angela Cenci   +5 more
doaj   +1 more source

Anatomical analysis of sensory ganglia in mice

Stress and Brain, 2022
Ganglia are nodular structures in the peripheral nervous system (PNS) that are formed by a cluster of neuron somas. They have important roles in communicating signals from peripheral organs to the nervous system and work as a unique structure of the PNS.
Meiqi Wang, Cheng Zhan
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment

npj Parkinson's Disease
Dopamine replacement therapy for Parkinson’s disease can induce impulsive-compulsive behaviours (ICBs). Here we compare the D2/3 agonist ropinirole and L-DOPA, given alone or combined, with regard to their potential to induce ICBs in rats sustaining ...
Mirjam Wolfschlag, Elena Espa, Katrine Skovgård, Pär Halje, Maria Angela Cenci   +4 more
doaj   +1 more source