Results 181 to 190 of about 441,395 (420)

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

open access: yesAdvanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini   +24 more
wiley   +1 more source

A Unified Model of Spatiotemporal Processing in the Retina [PDF]

open access: yes, 1992
A computational model of visual processing in the vertebrate retina provides a unified explanation of a range of data previously treated by disparate models.
Gaudiano, Paolo
core   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

open access: yesBioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells

open access: yesAdvanced Science, EarlyView.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová   +27 more
wiley   +1 more source

Ganglion blocks as a treatment of pain: current perspectives

open access: yesJournal of Pain Research, 2017
Osman Hakan Gunduz, Ozge Kenis-Coskun Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Marmara University, Istanbul, Turkey Abstract: The inputs from sympathetic ganglia have been known to be involved in the pathophysiology ...
Gunduz OH, Kenis-Coskun O
doaj  

Fast computation of the statistical significance test for spatio-temporal receptive field estimates obtained using spike-triggered averaging of binary pseudo-random sequences [PDF]

open access: yesarXiv
Background: Spatio-temporal receptive fields (STRF) of visual neurons are often estimated using spike-triggered averaging of binary pseudo-random stimulus sequences. The stimuli are visual displays that contain black and white pixels that flicker randomly at a fixed frame rate without any spatial or temporal correlation.
arxiv  

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