Results 131 to 140 of about 218,731 (306)
Advanced Science, EarlyView.Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han +10 more
wiley +1 more source
A Unified Quantitative Model of Vision and Audition [PDF]
, 2014 We have put forwards a unified quantitative framework of vision and audition, based on existing data and theories. According to this model, the retina is a feedforward network self-adaptive to inputs in a specific period.
Liu, Peilei, Wang, Ting
core +1 more source
Advanced Science, EarlyView.CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan +12 more
wiley +1 more source
Clinical Ophthalmology, 2016 Erkan Celik, Burcin Cakir, Elif Betul Turkoglu, Emine Doğan, Gursoy Alagoz Sakarya University Medical Education and Research Hospital, Sakarya, Turkey Purpose: We aimed to evaluate the effect of cataract surgery on subfoveal choroidal thickness (CT ...
Celik E +4 more
doaj
A model of ganglion axon pathways accounts for percepts elicited by retinal implants. [PDF]
, 2018 Degenerative retinal diseases such as retinitis pigmentosa and macular degeneration cause irreversible vision loss in more than 10 million people worldwide.
Beyeler, Michael +5 more
core
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Advanced Science, EarlyView.Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
Retina-imitation sampling based binary descriptor
Tongxin xuebao, 2019 The existing binary descriptors，generated from random or uniform point pairs sampling，suffer from low robustness and high computation.A novel sampling method,named RBS (retina-imitation based sampling),was proposed， which combines different densities ...
Qingsheng YUAN +3 more
doaj
The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
Advanced Science, EarlyView.Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková +5 more
wiley +1 more source