Results 121 to 130 of about 186,809 (300)

Setting limits: Ethical thresholds to the CEO-worker pay gap.

open access: yesPLoS ONE
In the discussion about wage inequality, principles of fairness and need for incentives are juxtaposed as opposing motivations for wage inequality acceptance.
Carmen Cervone   +3 more
doaj   +1 more source

A merging model for motorway traffic [PDF]

open access: yes, 2006
Motorway merging has long been regarded as a major source of conflicts and congestion on motorways. Traditional studies of merging behaviour are based on gap acceptance models developed mainly for urban intersections, which tend to oversimplify the very ...
Wang, Jiao
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Gap Acceptance at Two-Way Stop-Controlled Intersections

open access: yes, 1998
Gap Acceptance at Two-Way Stopped Controlled Intersections was written to develop gap acceptance values for two-way stop-controlled intersections. The specific objective was to assemble critical gap values, utilizing statistical analysis, that may be ...
Hagen, John M.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Generation gap in the workplace between Baby Boomers and Generation X [PDF]

open access: yes, 2001
Plan BGeneration gaps in perspectives, attitudes, and behaviors are nothing new, but they can be difficult to reconcile in the workplace. Lack of attention to generational differences will make any company less efficient; the critical management skills ...
Govitvatana, Wipanut Venique
core  

Models for pedestrian gap acceptance behaviour analysis at unprotected mid-block crosswalks under mixed traffic conditions

open access: yes, 2015
Pedestrian safety is an important aspect while crossing the road and it can be explained by pedestrian gap acceptance behaviour. The statistical models such as multiple linear regression (MLR) is often used to model linear relationships between dependent
RATHI, N, KADALI, BR, VEDAGIRI, P
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Gap Acceptance During Lane Changes by Large-Truck Drivers-An Image-Based Analysis. [PDF]

open access: yesIEEE trans Intell Transp Syst, 2016
Nobukawa K   +5 more
europepmc   +1 more source

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