A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Noise-induced instability of uniform flow in single-file traffic systems. [PDF]
Dufour O +5 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Minimum Vertex Cut with Reachable Set (MVCRS) Problem for Suppressing Botnet Propagation in IoT Networks: Complexity and Algorithms. [PDF]
Yamaguchi S.
europepmc +1 more source
Reducing culture underestimation in urine: flow cytometry-guided validation of low-dose DTT pre-treatment for biofilm dispersal. [PDF]
De La Motte LR +5 more
europepmc +1 more source
Comparison of post-treatment complications of conventional composites versus self-adhering composites: a review. [PDF]
Farshad F, Eskandari E, Rohaninasab M.
europepmc +1 more source
Data-Driven Optimization and Modelling of the Gap Bridgeability Performance of Multi-Pin Friction Stir Welded EN AW 7020-T651 Joints. [PDF]
Delir Nazarlou R +5 more
europepmc +1 more source
Engineering Plasma-Liquid Microdischarge Systems for Direct N<sub>2</sub>‑to-NH<sub>3</sub> Conversion at Ambient Conditions. [PDF]
Torre MF +8 more
europepmc +1 more source
Connexin 43-Enriched Vesicles Improve Synchronization in hiPSC-Derived Cardiomyocytes. [PDF]
Momtahan N +8 more
europepmc +1 more source

