Results 41 to 50 of about 14,103 (204)

Detection and quantification of active pharmaceutical ingredients as adulterants in Garcinia cambogia slimming preparations using NIR spectroscopy combined with chemometrics [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2020
A rapid, simple and efficient method with minimal sample treatment was developed for authentication of Garcinia cambogia fruit peel powder, along with determining undeclared active pharmaceutical ingredients (APIs) in its herbal slimming dietary ...
Rasha Abu El-Khair, Eman Shawky, Dina Selim   +2 more
doaj   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Late-stage halogenation of Scortechinone D via NaX oxidation and inhibitory activity against EGFR tyrosine kinase

Results in Chemistry
Three new scortechinone D derivatives (2–4) were effectively obtained through in situ halogenation of scortechinone D (1) using Oxone and sodium halide in a mixture of acetonitrile and water (5:1 ratio).
Ade Danova, Edwin Risky Sukandar, Rizky Annisa Ramadhini, Yusuf Eka Maulana, Elvira Hermawati, Fera Kurniadewi, Rita Hairani, Huong Thi Thu Le, Sutin Kaennakam, Warinthorn Chavasiri, Didin Mujahidin, Lia Dewi Juliawaty   +11 more
doaj   +1 more source

Neuraminidase Inhibitor of Garcinia atroviridis L. Fruits and Leaves Using Partial Purification and Molecular Characterization

Molecules, 2022
Neuraminidase (NA) is an enzyme that prevents virions from aggregating within the host cell and promotes cell-to-cell spread by cleaving glycosidic linkages to sialic acid.
Muchtaridi Muchtaridi, Rina Fajri Nuwarda, Emmy Hainida Khairul Ikram, Aisyah Saad Abdul Rahim, Amirah Mohd Gazzali, Habibah A. Wahab   +5 more
doaj   +1 more source

Building a genomic and herbarium biorepository for medicinal plants of the Western Ghats

PLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants support healthcare for millions of people and sustain livelihoods, yet many threatened species lack secure long‐term genetic protection. This study establishes a genomic and herbarium biorepository for medicinal plants of the Western Ghats, a global biodiversity hotspot facing intense human pressure.
Anurag Dhyani, Mathew Dan, Kalluvettankuzhy Krishnannair Sabu, Maniyannair Pankajakshiamma Geethakumary, Muhammed Abdul Jabbar, Sivankunju Suresh, Morgan R. Gostel   +6 more
wiley   +1 more source

Exploration of genetic variability in Garcinia [Garcinia gummi-gutta L.(Robson)] germplasm based on growth, yield and quality traits

Journal of Horticultural Sciences
Eleven Garcinia germplasm along with local check of Pechiparai were evaluated and underwent principal component analysis to assess genetic divergence and variation patterns during 2019 to 2022.
S T Bini Sundar, G Ashokkumar, A Jaya Jasmine, S Vasanth   +3 more
doaj   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Garcinia

The Journal of Primary Health Care, 2023
Aleksandra Milosavljevic, Jo Barnes
openaire   +4 more sources

Decrease of LDL Cholesterol Through The Increase of HDL Cholesterol by Administering Garcinia mangostana L. Peel Extract in White Mice

Folia Medica Indonesiana, 2021
Highlight: • Ethanol extract of Garcinia mangostana L. peel reduce malondialdehyde. • Garcinia mangostana L. peel extract can increase non-radical products which impact in decreasing LDL cholesterol and increasing HDL cholesterol.
Hasyim As'ari
doaj   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source