From Genomic and Epigenomic Maps to Medicines in Adult T-Cell Leukemia/Lymphoma. [PDF]
Cancer SciABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Suzuki K, Yamagishi M.
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GARP as a Therapeutic Target for the Modulation of Regulatory T Cells in Cancer and Autoimmunity
Frontiers in Immunology, 2022 Regulatory T cells (Treg) play a critical role in immune homeostasis by suppressing several aspects of the immune response. Herein, Glycoprotein A repetitions predominant (GARP), the docking receptor for latent transforming growth factor (LTGF-β), which ...
Niklas Zimmer +5 more
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GARP is regulated by miRNAs and controls latent TGF-β1 production by human regulatory T cells. [PDF]
PLoS ONE, 2013 GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface.
Emilie Gauthy +8 more
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Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. [PDF]
PLoS ONE, 2008 Regulatory T (T(reg)) cells control immune activation and maintain tolerance. How T(regs) mediate their suppressive function is unclear. Here we identified a cell surface molecule, called GARP, (or LRRC32), which within T cells is specifically expressed ...
Rui Wang +4 more
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GARP Regulates the Immune Capacity of a Human Autologous Platelet Concentrate
Biomedicines, 2022 Autologous platelet concentrates, like liquid platelet rich fibrin (iPRF), optimize wound healing; however, the underlying immunological mechanisms are poorly understood.
Emily R. Trzeciak +6 more
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Investigating the Effects of Frontotemporal Dementia‐Linked Genetic Mutations on Inequity Aversion Prior to Clinical Onset [PDF]
Alzheimers DementAbstract Background Frontotemporal dementia (FTD) is a neurodegenerative disorder associated with behavioral and cognitive impairments. This study hypothesized that individuals carrying FTD‐linked genetic mutations exhibit altered inequity aversion compared to non‐carriers, even before clinical symptoms emerge.
Wang C.
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Revealed Price Preference: Theory and Empirical Analysis [PDF]
, 2018 With the aim of determining the welfare implications of price change in consumption data, we introduce a revealed preference relation over prices.
Deb, Rahul +3 more
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Performance analysis in the coal bagging plant of Garp Lignite Corporation
Cogent Engineering, 2016 Companies can contribute to a country’s economy by means of efficient production in each of their units. The aim of this study was to examine the change in operational performance of the coal bagging plant of Garp Lignite Corporation in Turkey using the ...
Mehmet Nuri Bahşiş, Yaşar Kasap
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AÇIĞA ÇIKARILAN TERCİHLER: TEORİ VE UYGULAMA
Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2021 Türkiye’deki hanehalkları için açığa çıkarılan tercih teorisinin geçerliliğinin test edilmesinin, tüketici tercihlerindeki rasyonelliğin belirlenmesinin ve rasyonalitenin ihlal edilmesi durumunda ortaya çıkan refah kayıplarının ölçülmesinin amaçlandığı ...
Haydar Akyazı, Ozlem Ipek
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Becker random behavior and the as-if defense of rational choice theory in demand analysis [PDF]
, 2011 In discussing rational choice theory (RCT) as an explanation of demand behavior, Becker (1962, Journal of Political Economy, 70, 1–13) proposed a model of random choice in which consumers pick a bundle on their budget line according to a uniform ...
Moscati, Ivan, Tubaro, Paola
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