Mechanistic Insights into Alzheimer’s Disease Unveiled through the Investigation of Disturbances in Central Metabolites and Metabolic Pathways [PDF]
Hydrophilic metabolites are closely involved in multiple primary metabolic pathways and, consequently, play an essential role in the onset and progression of multifactorial human disorders, such as Alzheimer’s disease.
Raúl González-Domínguez+5 more
doaj +6 more sources
Gas-liquid chromatography-mass spectrometry of synthetic ceramides
Two series of ceramides with either sphingosine (sphing-4-enine) or sphinganine as base and with one of the saturated fatty acids C16, C18, C20, C22, C24, C26, or oleic acid were analyzed as the 1,3-di-O-trimethylsilyl ether derivatives by gas ...
Bengt Samuelsson, Karin Samuelsson
doaj +2 more sources
Peak Alignment of Gas Chromatography-Mass Spectrometry Data with Deep Learning [PDF]
We present ChromAlignNet, a deep learning model for alignment of peaks in Gas Chromatography-Mass Spectrometry (GC-MS) data. In GC-MS data, a compound's retention time (RT) may not stay fixed across multiple chromatograms. To use GC-MS data for biomarker discovery requires alignment of identical analyte's RT from different samples.
Li, Mike, Wang, X. Rosalind
arxiv +3 more sources
Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry [PDF]
The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors.
Maximilian Liebl+6 more
doaj +2 more sources
Application progress of gas chromatography-mass spectrometry in food analysis
Gas chromatography-mass spectrometry combines the advantages of efficient and rapid gas chromatography and accurate identification by mass spectrometry. Gas chromatography-mass spectrometry has been widely used in the separation and analysis of volatile ...
XING Qian-qian+3 more
doaj +1 more source
Research progress of HS-SPME-GC-MS in the detection of volatile substances in fruit products
From the perspective of the application of headspace solid-phase microextraction-mass spectrometry coupled with gas chromatography-mass spectrometry (HS-SPME-GC-MS) technology in the detection of volatile substances in fruit products, this paper ...
PANG Ji-wei+7 more
doaj +1 more source
Gas chromatography–mass spectrometry determination of deltamethrin in food
The article presents the results of the determination of the synthetic pyrethroid deltamethrin in raw food and various food products by gas chromatography with mass spectrometric detection (GC–MS).
I.M. Fitsev+4 more
doaj +1 more source
Detection of Urethane in Non-alcoholic Fermented Food [PDF]
Among fermented foods, urethane often appears, which is a “2A” grade carcinogen. There are many types of fermented foods in my country, and the detection methods are not uniform enough, and no specific urethane detection standards have been formed.
Lihua Zhang
doaj +1 more source
Native Mass Spectrometry and Nucleic Acid G-Quadruplex Biophysics: Advancing Hand in Hand [PDF]
While studying nucleic acids to reveal the weak interactions responsible for their three-dimensional structure and for their interactions with drugs, we also contributed to the field of biomolecular mass spectrometry, both in terms of fundamental understanding and with new methodological developments.
arxiv +1 more source
Recent Advances in Gas Chromatography [PDF]
Gas chromatography is one of the most used analytical techniques in the industry. It is a powerful tool with a wide range of applications. This book presents recent advances in gas chromatography, multidimensional gas chromatography, and gas ...
core +1 more source