Results 211 to 220 of about 334,028 (308)

Deazaflavin‐Catalyzed Arylation of White Phosphorus with Aryl Bromides and Chlorides

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The 5‐aryldeazaflavin photocatalyst o‐Me‐dFl catalyzes the arylation of white phosphorus with aryl chlorides and bromides under near UV‐LED irradiation, affording triarylphosphines and tetraarylphosphonium salts. Nuclear magnetic resonance studies and density functional theory calculations offer insights into the reaction pathway.
Jannes Rückel   +4 more
wiley   +1 more source

Iterative Use of Regiocomplementary Flavin‐Dependent Halogenases Gives Access to Unique Halogenation Patterns

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
The halide motif is ubiquitous in organic synthesis, facilitating fine‐tuning of molecular properties and functionalization using substitution and cross‐coupling reactions. Combination of different flavin‐dependent tryptophan halogenases enables the installation of novel halogenation patterns on l‐tryptophan, which can be orthogonally addressed in ...
Nicolai Montua   +4 more
wiley   +1 more source

Azabicyclo[1.1.0]butyl‐Substituted Sulfonimidoyl Fluoride: Electrophilic Hub Bridging Late‐Stage Azetidine Incorporation with Sufex Chemistry

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
GA: Strained small motifs and SuFEx hubs are of increasing importance in drug discovery to enable efficient late‐stage functionalization. Here, the synthesis of bench‐stable azabicyclo[1.1.0]butyl‐substituted sulfonimidoyl fluoride as an electrophilic hub with dual activation mode is reported.
Defne Serbetci   +5 more
wiley   +1 more source

Serum metabolic profiling of patients with diabetic kidney disease based on gas chromatography-mass spectrometry. [PDF]

open access: yesFront Mol Biosci
Bian X   +11 more
europepmc   +1 more source

THE DETERMINATION OF DIACETYL AND 2,3-PENTANEDIONE IN BEER HEAD SPACE BY GAS CHROMATOGRAPHY

open access: bronze, 1965
G.A. Harrison   +2 more
openalex   +1 more source

Redrawing the Mannich‐Type Reaction through Carbonyl Umpolung Reactivity

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
GA: Herein, a conceptually novel one‐pot multicomponent strategy is reported for the streamlined construction of five‐membered imidazolidines from 1,2‐diaza‐1,3‐dienes (onefold), amines (twofold), and formaldehyde (twofold). This redesigned Mannich‐type reaction that exploits a carbene‐like activity of 1,2‐diaza‐1,3‐dienes (realized by “umpolung ...
Vittorio Ciccone   +4 more
wiley   +1 more source

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