Gas phase ion chemistry of an ion mobility spectrometry based explosive trace detector elucidated by tandem mass spectrometry [PDF]
Talanta, 2015 The gas phase ion chemistry for an ion mobility spectrometer (IMS) based explosive detector has been elucidated using tandem mass spectrometry. The IMS system, which is operated with hexachloroethane and isobutyramide reagent gases and an ion shutter type gating scheme, is connected to the atmospheric pressure interface of a triple quadrupole mass ...
Jason R Stairs
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Computational insights into compaction of gas-phase protein and protein complex ions in native ion mobility-mass spectrometry [PDF]
TrAC - Trends in Analytical Chemistry, 2019 Native ion mobility-mass spectrometry (IM-MS) is a rapidly growing field for studying the composition and structure of biomolecules and biomolecular complexes using gas-phase methods. Typically, ions are formed in native IM-MS using gentle nanoelectrospray ionization conditions, which in many cases can preserve condensed-phase stoichiometry.
James S Prell, Amber D Rolland
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JACS AuProtein activity depends on motional transitions between conformational states. Modifications or ligand binding can alter protein dynamics, leading to changes in activity. Established biophysical methods effectively determine protein structures but face challenges when investigating dynamic biological processes that involve steady states of transiently
Fanny C. Liu +6 more
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Perspective on Developments in Ion Mobility Spectrometry-Mass Spectrometry Combined with Ion Spectroscopy [PDF]
Zhipu Xuebao, 2022 Combined with mass spectrometry, ion spectroscopy can obtain a spectrum of the target ion by measuring its intensity change, which is induced by laser strength and wavelength.
WANG Na1 +5 more
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Ion Mobility-Mass Spectrometry and its Applications in Protein Glycosylation Research [PDF]
Zhipu Xuebao, 2022 Glycosylation is one of the most important post-translational modifications (PTM), mediating physiological processes like cell adhesion, cell proliferation, cell signaling, and immune responses.
FU Bin1, LIANG Yu-ying1, LU Hao-jie1,2
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Method and Applications of Ion Collision Cross Section Measurement Based on Fourier Transform-Ion Cyclotron Resonance [PDF]
Zhipu Xuebao, 2022 The measurement of gas phase collision cross section (CCS) of ions can provide complementary structure information to those typically obtained from mass spectrometry or tandem mass spectrometry.
ZHANG Kai-lin1 +7 more
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Recent Progress in Protein Stereochemical Modifications Revealed by Ion Mobility-Mass Spectrometry [PDF]
Zhipu Xuebao, 2022 Protein stereochemical modification (SCM) is a unique type of low-abundance post-translational modification associated with many human diseases. Because it does not change the molecular weight of proteins, traditional proteomics methods are generally not
XU Xia1 +3 more
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Shipin gongye ke-ji, 2022 In order to study the effect of vacuum cooling on the volatile components of beef seasoned with soysauce, the volatile components of beef with and without vacuum cooling were qualitatively and quantitatively analyzed by HS-SPME-GC-MS (headspace solid ...
CAO Weifeng +3 more
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Frontiers in Molecular Biosciences, 2023 It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids is critical to better understand their roles in biological processes.
Sandra M. Camunas-Alberca +6 more
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New Development in Ion Mobility Spectrometry for Analysis of Small Molecule Isomers [PDF]
Zhipu Xuebao, 2022 With the rapid development of modern detection technology and scientific research, the chemical structures and functions of isomers are constantly being revealed.
WU Fang-ling1 +4 more
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