Results 11 to 20 of about 7,759,429 (252)

Gas Phase Stability of Protein Ions in a Cyclic Ion Mobility Spectrometry Traveling Wave Device [PDF]

open access: yesAnalytical Chemistry, 2018
Ion mobility mass spectrometry (IM-MS) allows separation of native protein ions into “conformational families”. Increasing the IM resolving power should allow finer structural information to be obtained, and can be achieved by increasing the length of the IM separator.
Charles Eldrid   +6 more
openaire   +7 more sources

Native Ion Mobility Mass Spectrometry: When Gas-Phase Ion Structures Depend on the Electrospray Charging Process [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2018
Ion mobility spectrometry (IMS) has become popular to characterize biomolecule folding. Numerous studies have shown that proteins that are folded in solution remain folded in the gas phase, whereas proteins that are unfolded in solution adopt more extended conformations in the gas phase. Here, we discuss how general this tenet is.
Khristenko, Nina   +5 more
openaire   +7 more sources

Gas-Phase Chiral Separations by Ion Mobility Spectrometry [PDF]

open access: yesAnalytical Chemistry, 2006
This article introduces the concept of chiral ion mobility spectrometry (CIMS) and presents examples demonstrating the gas-phase separation of enantiomers of a wide range of racemates including pharmaceuticals, amino acids, and carbohydrates. CIMS is similar to traditional ion mobility spectrometry, where gas-phase ions, when subjected to a potential ...
Prabha, Dwivedi   +5 more
openaire   +4 more sources

Mass spectrometric analysis of pilus assembly, amyloid fibril formation, and membrane proteins in their native state [PDF]

open access: yes, 2012
Structural analysis of proteins and their complexes is crucial to understanding protein function. This thesis demonstrates the application of mass spectrometry (MS) to the study of pilus assembly on Gram-negative bacteria and amyloid formation in ...
Leney, Aneika Corrine
core   +6 more sources

Glycan analysis by ion mobility-mass spectrometry and gas-phase spectroscopy [PDF]

open access: yesCurrent Opinion in Chemical Biology, 2018
Due to the existence of numerous isomers, the in-depth analysis of glycans represents a major challenge. Currently, the majority of glycans are analysed using mass spectrometry (MS)-based techniques, which can provide information on regioisomers but usually fail to differentiate stereoisomers.
Manz, C., Pagel, K.
openaire   +3 more sources

Determining the gas-phase structures of α-helical peptides from shape, microsolvation, and intramolecular distance data

open access: yesNature Communications, 2023
Mass spectrometry is a powerful technique for the structural and functional characterization of biomolecules. However, it remains challenging to accurately gauge the gas-phase structure of biomolecular ions and assess to what extent native-like ...
Ri Wu   +10 more
doaj   +1 more source

Univariate and multivariate DMS calibration for a single analyte [PDF]

open access: yesE3S Web of Conferences, 2019
Differential mobility spectrometry (DMS) is a promising measurement technique. It is used in the detection of chemical warfare agents, explosives, drugs, and volatile organic compounds.
Szczurek Andrzej   +2 more
doaj   +1 more source

Low-cost Arduino controlled dual-polarity high voltage power supply

open access: yesHardwareX, 2023
Ion Mobility Spectrometry (IMS) provides low ppbv detection limits for gas-phase or aqueous analytes. These instruments rely an electric field to produce ion motion.
Eric J. Davis, Brian H. Clowers
doaj   +1 more source

Discrimination of different edible vegetable oils based on GC-IMS and SIMCA

open access: yesCyTA - Journal of Food, 2023
Ion mobility spectrometry coupled to gas-chromatographic (GC-IMS) is tested regarding their ability to analyze various refined edible vegetable oils, including sunflower seed, rapeseed, sesame, soybean, peanut, corn, camellia, linseed, walnut, coconut ...
Dechun Geng   +3 more
doaj   +1 more source

Discrimination and Characterization of the Volatile Organic Compounds in Schizonepetae Spica from Six Regions of China Using HS-GC-IMS and HS-SPME-GC-MS

open access: yesMolecules, 2022
Volatile organic compounds (VOCs) are the main chemical components of Schizonepetae Spica (SS), which have positive effects on the quality evaluation of SS.
Chao Li   +10 more
doaj   +1 more source

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