αvβ3-targeted gas vesicles for ultrasound molecular imaging of tumors [PDF]
Frontiers in Bioengineering and BiotechnologyPurposeTo achieve ultrasound molecular imaging (UMI) of various tumor types, this study developed a novel integrin-targeted probe, RGD-hGVs, based on gas vesicles (GVs) derived from Halobacterium salinarum NRC-1 (Halo) and cyclic RGDfK peptides.
Xiong Shen +13 more
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Gas vesicles in actinomycetes: old buoys in novel habitats? [PDF]
Trends in Microbiology, 2005 Gas vesicles are gas-filled prokaryotic organelles that function as flotation devices. This enables planktonic cyanobacteria and halophilic archaea to position themselves within the water column to make optimal use of light and nutrients. Few terrestrial microbes are known to contain gas vesicles.
Keulen, Geertje van +3 more
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Ultrasound Imaging Properties of Heterologously Synthesized Gas Vesicles from Halophilic Archaeon [PDF]
NanomaterialsBiosynthetic gas vesicles (GVs), as novel nanoscale ultrasound contrast agents, exhibit unique potential in biomedical ultrasound imaging. For example, they are expected to have better tissue penetration through the tumor vasculature for detecting tumor ...
Wenze Ou +6 more
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Ultrasound contrast agents from microbubbles to biogenic gas vesicles [PDF]
Medical Review, 2023 Microbubbles have been the earliest and most widely used ultrasound contrast agents by virtue of their unique features: such as non-toxicity, intravenous injectability, ability to cross the pulmonary capillary bed, and significant enhancement of echo ...
Zeng Wenlong, Yue Xiuli, Dai Zhifei
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The Function of Gas Vesicles in Halophilic Archaea and Bacteria: Theories and Experimental Evidence
Life, 2012 A few extremely halophilic Archaea (Halobacterium salinarum, Haloquadratum walsbyi, Haloferax mediterranei, Halorubrum vacuolatum, Halogeometricum borinquense, Haloplanus spp.) possess gas vesicles that bestow buoyancy on the cells. Gas vesicles are also
Aharon Oren
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Screening and Evaluation of Chassis Cells for Heterologous Biosynthesis of Gas Vesicles as Ultrasound Contrast Agents [PDF]
Marine DrugsGas vesicles (GVs) are hollow protein nanostructures derived from microorganisms and show significant potential for ultrasound imaging applications. However, the direct production of gas vesicles (GVs) from their native hosts faces several limitations ...
Qiuxia Fu +7 more
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The model cyanobacteria Anabaena sp. PCC 7120 possess an intact but partially degenerated gene cluster encoding gas vesicles [PDF]
BMC Microbiology, 2020 Background Bacterial gas vesicles, composed of two major gas vesicle proteins and filled with gas, are a unique class of intracellular bubble-like nanostructures. They provide buoyancy for cells, and thus play an essential role in the growth and survival
Kun Cai +6 more
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, 2019 Mega gas vesicles, purified, -1 to -5 micron defocus. Reconstruct with included scripts for ctf-corrected bin1 tomogram.<strong>Tilt Series Date:</strong> 2019-09-25</p> <strong>Data Taken By:</strong> LaurenAnn Metskas< ...
Metskas, LaurenAnn
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Characterization and Comparison of Contrast Imaging Properties of Naturally Isolated and Heterologously Expressed Gas Vesicles [PDF]
PharmaceuticalsNanoscale ultrasound contrast agents have attracted considerable interest in the medical imaging field for their ability to penetrate tumor vasculature and enable targeted imaging of cancer cells by attaching to tumor-specific ligands.
Tingting Liu +5 more
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Surface-engineered bio-manufactured gas vesicles for multimodal imaging of glioma [PDF]
Journal of NanobiotechnologyIntegrated imaging techniques offer enhanced medical insights into the central nervous system by combining different modalities. In glioma diagnosis, the challenge often lies in delivering contrast agents effectively across the blood-brain barrier.
Juanjuan Li +8 more
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