Results 221 to 230 of about 3,607 (251)

Gasdermin E-mediated intestinal epithelial pyroptosis promotes chemically induced colitis in mice. [PDF]

Gastroenterol Rep (Oxf)
Wu YZ, Xie Y, Chen L, Ning L, Hu XQ, Xu XP.   +5 more
europepmc   +1 more source

A CD4+ T lymphocyte-specific TCR/GSDMD/IL-2 axis facilitates antitumor immunity. [PDF]

J Clin Invest
Yao Y, Wang L, Jiang W, Wang N, Li M, Lin W, Zhang T, Sheng W, Wang X.   +8 more
europepmc   +1 more source

Gasdermin D (GSDM D) as a Potential Diagnostic Biomarker in Bladder Cancer: New Perspectives in Detection. [PDF]

Cancers (Basel)
Gudowska-Sawczuk M, Pączek S, Olkowicz M, Kudelski J, Mroczko B.   +4 more
europepmc   +1 more source

GSDME in cardiovascular diseases: research system and contemporary progress. [PDF]

Front Immunol
Yang Z, Luo Z, Zhang H, Zong J, Huang P, Niu Y, Zhou C, Wang S, Zhang D.   +8 more
europepmc   +1 more source

Emerging Insights into the Interplay Between PANoptosis and Autophagy in Immune Regulation and Immune-Mediated Inflammatory Diseases. [PDF]

Med Sci (Basel)
Sipos F, Műzes G.
europepmc   +1 more source

Reviewer #2 (Public review): Gasdermin D-mediated neutrophil pyroptosis drives inflammation in psoriasis

openalex   +1 more source

Macrophage gasdermin A (GSDMA) in systemic sclerosis.

, 2019
Moreno-Mora, Aida, Bagnati, Marta, Kotura, Surya, Jeong-Hun Ko, Fonseca, Carmen, Harmston, Nathan, Game, Laurence, Martín, Javier, Ong, Voon, Abraham, David J., Denton, Christopher, Petretto, Enrico, Behmoaras, Jacques   +12 more
openaire   +1 more source

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Gasdermins and cancers

Seminars in Immunology, 2023
The identification of gasdermin as the executor of pyroptosis has opened new avenues for the study of this process. Although pyroptosis research has mainly focused on immune cells since it was discovered three decades ago, accumulating evidence suggests that pyroptosis plays crucial roles in many biological processes.
Junwei Hou, Tiansheng Li, Jung-Mao Hsu, Xin Zhang, Mien-Chie Hung   +4 more
openaire   +2 more sources

Gasdermin D kills bacteria

Microbiological Research, 2023
The recognition of pathogen- or damage- associated molecular patterns (PAMPs/DAMPs) signals a series of coordinated responses as part of innate immunity or host cell defense during infection. The inflammasome is an assemblage of multiprotein complexes in the cytosol that activate inflammatory caspases and release pro-inflammatory mediators. This review
Abosede Salami, Sahana Bettadapura, Shanzhi Wang   +2 more
openaire   +2 more sources

Inducing Pyroptosis via Gasdermin B and Gasdermin E Cleavage

2023
Gasdermin B (GSDMB) and gasdermin E (GSDME) are two members of the gasdermin family, which shares a conservative gasdermin-N domain capable of executing pyroptotic cell death, through perforating the plasma membrane from inside of the cell. Both GSDMB and GSDME are autoinhibited in the resting stage and require proteolytic cleavage to unleash the pore ...
Zhiwei, Zhou, Yupeng, Wang, Feng, Shao
openaire   +2 more sources