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Assessing the Effectiveness of Eslicarbazepine Acetate in Reducing Audiogenic Reflex Seizures in the GASH/Sal Model of Epilepsy [PDF]

open access: yesBiomedicines
Eslicarbazepine acetate (ESL) is a third-generation antiepileptic drug indicated as monotherapy for adults with newly diagnosed epilepsy and as adjunctive therapy for the treatment of partial seizures.
Jaime Gonçalves-Sánchez   +4 more
doaj   +5 more sources

Comparison of revised Gash models for estimating rainfall interception in an oriental beech stand, west of Hyrcanian region [PDF]

open access: yesمجله جنگل ایران, 2022
The most common models for estimating rainfall interception are physical-based models, of which Gash models are the most widely used. Therefore, this study aimed to compare the efficiency of revised Gash models in estimating the rainfall interception of ...
K. Sefidi, S.M.M. Sadeghi
doaj   +2 more sources

Behavioral and Molecular Effects Induced by Cannabidiol and Valproate Administration in the GASH/Sal Model of Acute Audiogenic Seizures [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2021
Despite evidence that supports cannabidiol (CBD) as an anticonvulsant agent, there remains controversy over the antiseizure efficacy, possible adverse effects, and synergistic interactions with classic antiepileptics such as valproate (VPA).
Giselda Cabral-Pereira   +22 more
doaj   +4 more sources

Anticonvulsant effects, safety, and sex-dependent molecular signatures of cannabidiol treatment in a preclinical model of audiogenic epilepsy [PDF]

open access: yesFrontiers in Pharmacology
Roughly one-third of patients with epilepsy remain drug resistant, underscoring the need for novel therapeutic strategies. Although cannabidiol (CBD) has recently been approved for specific epileptic encephalopathies, its anticonvulsant mechanisms and ...
Giselda Cabral-Pereira   +8 more
doaj   +2 more sources

Modeling vegetation interception under natural rainfall in yerba mate production systems [PDF]

open access: yesRBRH, 2023
Interception loss plays an important role in rainfall partitioning, retaining significant amounts of water that would be directed to the soil. In this work, the objective was to measure interception by vegetation and evaluate the Rutter and Gash models ...
Ezequias Rodrigues dos Santos   +2 more
doaj   +1 more source

Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal

open access: yesFrontiers in Behavioral Neuroscience, 2021
The endocannabinoid system modulates epileptic seizures by regulating neuronal excitability. It has become clear that agonist activation of central type I cannabinoid receptors (CB1R) reduces epileptogenesis in pre-clinical animal models of epilepsy. The
Alejando Fuerte-Hortigón   +14 more
doaj   +1 more source

Proteomic and Bioinformatic Tools to Identify Potential Hub Proteins in the Audiogenic Seizure-Prone Hamster GASH/Sal

open access: yesDiagnostics, 2023
The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca) is a model of audiogenic seizures with the epileptogenic focus localized in the inferior colliculus (IC).
Carlos García-Peral   +5 more
doaj   +1 more source

Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal

open access: yesFrontiers in Neurology, 2020
The Wistar Audiogenic Rat (WAR) and the Genetic Audiogenic Seizure Hamster from Salamanca (GASH/Sal) strains are audiogenic epilepsy models, in which seizures are triggered by acoustic stimulation.
Samara Damasceno   +8 more
doaj   +1 more source

Inferior Colliculus Transcriptome After Status Epilepticus in the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal

open access: yesFrontiers in Neuroscience, 2020
The Genetic Audiogenic Seizure Hamster from Salamanca (GASH/Sal), an animal model of reflex epilepsy, exhibits generalized tonic–clonic seizures in response to loud sound with the epileptogenic focus localized in the inferior colliculus (IC).
Sandra M. Díaz-Rodríguez   +14 more
doaj   +1 more source

Rainfall interception using the revised Gash analytical model for Pinus sylvestris var. mongolica in a semi-humid region of NE China

open access: yesEcological Indicators, 2022
Rainfall loss by canopy interception comprises a substantial portion of the water budget in forested ecosystems, and accurately measuring and simulating this process is critical for the effective management of forest water resources. Pinus sylvestris var.
Jifeng Deng   +6 more
doaj   +1 more source

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