Assessing the Effectiveness of Eslicarbazepine Acetate in Reducing Audiogenic Reflex Seizures in the GASH/Sal Model of Epilepsy [PDF]
BiomedicinesEslicarbazepine acetate (ESL) is a third-generation antiepileptic drug indicated as monotherapy for adults with newly diagnosed epilepsy and as adjunctive therapy for the treatment of partial seizures.
Jaime Gonçalves-Sánchez +4 more
doaj +5 more sources
Proteomic and Bioinformatic Tools to Identify Potential Hub Proteins in the Audiogenic Seizure-Prone Hamster GASH/Sal [PDF]
Diagnostics, 2023 The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca) is a model of audiogenic seizures with the epileptogenic focus localized in the inferior colliculus (IC).
Carlos García-Peral +5 more
doaj +2 more sources
Event-Based Rainfall Interception Modeling in a Cerrado Riparian Forest—Central Brazil: An Alternative Approach to the IS Method for Parameterization of the Gash Model [PDF]
Water (Switzerland), 2020 Although being the second largest biome in South America, the Cerrado biome is understudied in terms of hydrological modeling of the interception processes of its different vegetation types. To better understand its net precipitation components, high-temporal-resolution throughfall data were used to parameterize the Gash Analytical Model on a per storm
Sérgio Koide
exaly +2 more sources
Effect of initial plant density on modeling accuracy of the revised sparse Gash model: a case study of Pinus tabuliformis plantations in northern China [PDF]
Hydrology Research, 2020 An accurate quantitative description of interception is necessary to understand regional water circulation. The revised sparse Gash model (RSGM) is currently used to estimate interception loss.
Yiran Li +5 more
doaj +2 more sources
Changes in the Proteomic Profile After Audiogenic Kindling in the Inferior Colliculus of the GASH/Sal Model of Epilepsy [PDF]
International Journal of Molecular SciencesEpilepsy is a multifaceted neurological disorder characterized by recurrent seizures and associated with molecular and immune alterations in key brain regions. The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca), a genetic model for audiogenic epilepsy, provides a powerful tool to study seizure mechanisms and resistance in predisposed ...
Laura Zeballos +5 more
openaire +4 more sources
Forest Ecology and Management, 2018 Abstract Interception represents a significant component of the water budget of forests, diverting significant quantities of precipitation away from soil moisture, transpiration, and surface and groundwater recharge. There are several physically-based models of forest interception but their utility across seasonal variability is limited because few ...
Omid Fathizadeh
exaly +4 more sources
A Modified Gash Model for Estimating Rainfall Interception Loss of Forest Using Remote Sensing Observations at Regional Scale [PDF]
Water (Switzerland), 2014 Rainfall interception loss of forest is an important component of water balance in a forested ecosystem. The Gash analytical model has been widely used to estimate the forest interception loss at field scale. In this study, we proposed a simple model to estimate rainfall interception loss of heterogeneous forest at regional scale with several ...
, Yaokui Cui, Cui Yaokui
exaly +2 more sources
Forests, 2022 Canopy interception is an important part of forest ecosystem hydrological processes. It is the first stage of water distribution when rainfall reaches the canopy and has an important impact on nutrient inputs and water exchange. Pinus tabulaeformis is a main tree species in the rocky mountain areas of Northern China, and it is also a primary species ...
Qian, Yunkai +5 more
exaly +2 more sources
Journal of Hydrology: Regional StudiesStudy region: The Gash aquifer, located in the drought-prone Kassala region of eastern Sudan Study focus: Groundwater resources face growing global threats from over-extraction, limited recharge, and climate change—especially in arid and semi-arid ...
Mojahid Almahi, Haishen Lü, Yonghua Zhu
doaj +2 more sources
Audiogenic Kindling Stimulation Fails to Induce Cerebral Overexpression of P-Glycoprotein and Limbic Crises in the GASH/Sal Model of Epilepsy [PDF]
International Journal of Molecular SciencesExperimental evidence indicates that a high seizure burden can induce cerebral overexpression of P-glycoprotein (P-gp) at the blood–brain barrier, a phenomenon associated with drug-resistant epilepsy under the “transporter hypothesis”, but also at the neuronal level, linked to a reduced seizure threshold, increased seizure severity (SS), status ...
Zeballos Fernández, Laura +3 more
openaire +3 more sources