Assessment of the Relationship Between Gastric-Acid Suppressants and the Risk of Esophageal Adenocarcinoma: A Systematic Review and Meta-Analysis [PDF]
Current Therapeutic Research, 2023 : Background: Esophageal cancer is a cancerous tumor that develops in the esophagus. It is the 10th most common cancer and has a low survival rate. Esophageal adenocarcinoma (EAC) is increasing in incidence globally.
Karamali Kasiri, Associate +3 more
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Effect of simulated gastric acid on the mechanical properties of conventional and polypropylene mesh reinforced poly methyl methacrylate denture base resin [PDF]
The Journal of Indian Prosthodontic SocietyAim: Sustainability of dental polymethyl methacrylate (PMMA) in acidic environments is crucial as oral pH fluctuations can degrade the mechanical properties of denture bases.
Abhinaya Bollepalli +2 more
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Carbohydrate intake and activation of gastric acid secretion decrease gastric estrogen secretion [PDF]
Scientific ReportsGastric parietal cells (gastric acid-secreting cells) secrete estrogen in response to blood lipid (triglycerides [TG] and fatty acids [FFA]) levels. Since estrogen helps reduce blood lipid levels, gastric estrogen would be important in lowering elevated ...
Takao Ito +3 more
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Transcriptome Sequencing Reveals Survival Strategies and Pathogenic Potential of Vibrio parahaemolyticus Under Gastric Acid Stress [PDF]
BiologyAs a common food-borne pathogen, Vibrio parahaemolyticus comes into direct or indirect contact with gastric acid after ingestion. However, the mechanisms by which Vibrio parahaemolyticus passes through the gastric acid barrier, recovers, and causes ...
Shiying Ji +8 more
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Potassium-competitive Acid Blockers: A New Therapeutic Strategy for Helicobacter pylori Eradication [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023 The escalating prevalence of clarithromycin resistance in cases of Helicobacter pylori, insufficient acid suppression, and pharmacodynamic variations secondary to inter-individual differences in CYP2C19 polymorphism collectively contribute to suboptimal ...
Byeong Yun Ahn, Soo-Jeong Cho
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Treatment of Acid-related Diseases Using Potassium-competitive Acid Blockers
The Korean Journal of Gastroenterology, 2022 Proton pump inhibitors (PPIs) have several limitations to their efficacy including insufficient acid suppression, slow onset of action, and variable efficacy among patients due to CYP2C19 metabolism.
Yoon Jin Choi
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Effect of Combination Therapy of Oral Famotidine with Mosapride on Intragastric pH and Gastric Emptying in Rats [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2021 Background/Aims Studies in healthy humans have reported that the addition of mosapride to acid suppressants resulted in higher intragastric pH than acid suppressant administration alone.
Hyun Seok Choi +6 more
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Comparison of the Effects of Oral Nizatidine versus Famotidine on Intragastric pH and Gastric Emptying in a Stress Rat Model [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022 Background/Aims Histamine-2 receptor antagonists (H2RA) are used to treat acid-related disorders and functional dyspepsia. In contrast to other H2RAs, nizatidine promotes gastric emptying (GE).
Dong Han Yeom +6 more
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Floating Microballoons of Rhynchosia densiflora Leaf Extract for the Treatment of Peptic Ulcer [PDF]
Trends in Pharmaceutical Sciences, 2022 Peptic ulcer is one of the most common gastrointestinal problems diagnosed all over the world. The aim of the present study is to develop floating microballoons of Rhynchosia densiflora (Roth) DC leaf extract and to evaluate its peptic ulcer activity. An
Devadath NG +3 more
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Endoscopic Characteristics of Rugal Hyperplasia and Related Acid Condition in Helicobacter pylori-Infected Stomach [PDF]
Clinical Endoscopy, 2021 Background/Aims Rugal hyperplastic gastritis (RHG) is associated with Lauren’s diffuse-type gastric cancer (GC) and the accompanying active inflammation is linked to gastric hypoacidity.
Byung Chul Kim, Mi Ae Song, Sung Ho Kwon
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