Results 31 to 40 of about 310,995 (161)
Journal of Medicinal Plants, 2008 Background: It has been clearly documented that Elaegnaceae have a variety of medicinal uses including anti-ulcerogenic activity. Objective: We therefore hypothesized that Elaeagnus angustifulia L. (E.
A Eliassi, M Mandipour, M Kamalinejad
doaj
Frontiers in PharmacologyIntroductionThe aim of this study is to characterize the pharmacology of linaprazan glurate (X842), an ethyl ester prodrug of linaprazan (a novel potassium-competitive acid blocker), in animal species in vitro and in vivo to achieve a better ...
Ming Lu +9 more
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Carnosic Acid Induces Apoptosis and Inhibits Akt/mTOR Signaling in Human Gastric Cancer Cell Lines
Pharmaceuticals, 2021 Gastric cancer is among the most common malignancies worldwide. Due to limited availability of therapeutic options, there is a constant need to find new therapies that could target advanced, recurrent, and metastatic gastric cancer.
Waseem El-Huneidi +8 more
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Frontiers in Microbiology, 2023 ObjectiveBile reflux plays a key role in the development of gastric intestinal metaplasia (GIM), an independent risk factor of gastric cancer. Here, we aimed to explore the biological mechanism of GIM induced by bile reflux in a rat model.MethodsRats ...
Zijing Xu +8 more
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Motilin Stimulates Gastric Acid Secretion in Coordination with Ghrelin in Suncus murinus. [PDF]
PLoS ONE, 2015 Motilin and ghrelin constitute a peptide family, and these hormones are important for the regulation of gastrointestinal motility. In this study, we examined the effect of motilin and ghrelin on gastric acid secretion in anesthetized suncus (house musk ...
Chayon Goswami +7 more
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Effect of gastric acid‐reducing agents on the pharmacokinetics and efficacy of lemborexant
Pharmacology Research & Perspectives, 2020 Lemborexant is a dual orexin receptor antagonist approved for treating insomnia. As the solubility of lemborexant is pH‐sensitive, the impact of the gastric acid‐reducing agent (ARA), famotidine, on lemborexant pharmacokinetics was evaluated in a Phase 1
Ishani Landry +6 more
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Roles and action mechanisms of bile acid-induced gastric intestinal metaplasia: a review
Cell Death Discovery, 2022 Gastric intestinal metaplasia (IM) is a precancerous lesion that increases the risk of subsequent gastric cancer (GC) development. Therefore, the mechanism of IM has been the focus of basic and clinical research. Helicobacter pylori (H. pylori) infection
Qijin He +7 more
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The Saudi Journal of Gastroenterology, 2008 Background/Aim: Previous studies on "Black seed" or "Black Cumin" Nigella sativa (NS) have reported a large number of pharmacological activities including its anti-ulcer potential.
Al Mofleh Ibrahim +6 more
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浙江大学学报. 农业与生命科学版, 2005 Thirty crossbred weanling piglets with an average initial weight of 5.25 kg, weaned at (28±1) d of age, were divided into five groups to determine the effect of hydrochloric acid (HCl) and sodium bicarbonate (NaHCO3) supplementation on gastric acid ...
LENG Xiang-jun +4 more
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Microribonucleic acids and gastric cancer [PDF]
Cancer Science, 2012 Gastric carcinogenesis is a multistep process involving genetic and epigenetic alteration of protein‐coding proto‐oncogenes and tumor‐suppressor genes. Microribonucleic acids (miR) are a recently‐described class of genes encoding small non‐coding RNA molecules, which primarily act by downregulating the translation of target mRNA. It has become apparent
Ying-Yu, Ma, Hou-Quan, Tao
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