Results 141 to 150 of about 512,062 (356)

Protective effect of oleic acid against acute gastric mucosal lesions induced by ischemia-reperfusion in rat

open access: yesThe Saudi Journal of Gastroenterology, 2007
Aim: To assess the effect of Linoleic acid and oleic acid on gastric lesions induced by ischemia reperfusion. Materials and Methods: Twenty-six fasted rats were subjected to 30 minutes of gastric ischemia in the presence of 100 mmol/L hydrochloric ...
Alzoghaibi Mohammed
doaj  

Inhibition of Acid Secretion in Gastric Parietal Cells by the Ca2+/ Calmodulin-Dependent Protein Kinase II Inhibitor KN-93.

open access: diamond, 1994
Naoto Mamiya   +6 more
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

A spectrophotometric study of blood group A-specific substance isolated from hog gastric mucosa [PDF]

open access: yes, 1948
A study of the ultraviolet absorption spectra of preparations of blood group A-specific substance isolated from hog gastric mucin supports the view that group A substance, and probably group O substance, has little specific absorption in this spectral ...
Holzman, George, Niemann, Carl
core  

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

open access: yesAdvanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen   +14 more
wiley   +1 more source

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system. [PDF]

open access: yes, 2019
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Akiba, Yasutada   +2 more
core  

Halofuginone is a Molecular Glue Degrader of Integrin β4

open access: yesAdvanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong   +8 more
wiley   +1 more source

Effect of esophageal distention on basal and stimulated gastric acid secretion in rats

open access: yesIranian South Medical Journal, 2007
Background: It is well established that the esophageal distention leads to gastric relaxation, partly by vago-vagal reflex but till now, the effect of esophageal distention on gastric acid secretion has not been investigated. The aim of this study was to
Mohammad Kazem Gharib Nasery   +2 more
doaj  

Relationship between gastric acid and elevated plasma somatostatinlike immunoreactivity after a mixed meal

open access: bronze, 1989
Michael R. Lucey   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy