Results 151 to 160 of about 512,062 (356)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Intracerebroventricularly Administered Nicotine Inhibits Vagally Stimulated Gastric Acid Output in Rats by Activating the Central Sympatho-Adrenal Outflow

, 1987
Kunihiko YOKOTANI, Yasunobu Okuma, Yoshitsugu Osumi   +2 more
openalex   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

An experimental study of the ileo-jejunal transposition on the influence of canine gastric acid secretion and gut hormones.

, 1990
Morihiko Toda, Iwao Sasaki, Hiroo Naito, Michinaga Takahashi, Seiki Matsuno   +4 more
openalex   +2 more sources

EFFECTS OF ASPIRIN‐LIKE DRUGS ON CANINE GASTRIC MUCOSAL BLOOD FLOW AND ACID SECRETION [PDF]

, 1977
A. B. Bennett, B P Curwain
openalex   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

Advanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang, Xi Dai, Shuaihu Li, Yingxue Chen, Yaxin Yu, Lin Wang, Kun Liu, Shuhan Lyu, Chongyang Li, Yihua Sun, Fei Li   +10 more
wiley   +1 more source

Proton Pump Activation in Stimulated Parietal Cells Is Regulated by Gastric Acid Secretory Capacity: A Human Study

, 2002
David C. Metz, Géraldine M. Ferron, Jeffrey Paul, Mary Beth Turner, Elaine Soffer, Joseph R. Pisegna, Wieslaw Bochenek   +6 more
openalex   +2 more sources

Gastric ulcers, blood groups, and acid secretion [PDF]

, 1964
A Bucko, A Dvorsky, J Cottet, A Dawson, K Isselbacher, M Demole, M Arpin-Morand, E Fedor, B Fisher, E Ginter, P Bobek, Z Blalek, J Cerveh, J Heersma, J Annegers, L Holt, H Tidwell, C Kirk, D Cross, Neale, S, A Ivy, C Jones, P Culver, G Drummey, A Ryan, Van Kamer, J De, H Huinink, Bokkel, H Weyers, A Krondl, V Bohdalova, F Minard, H Redetzki, R Gronow, L Stern, B Shapiro, H Tidwell, M Nagler   +39 more
openalex   +1 more source

18β-glycyrrhetinic acid promotes gastric cancer cell autophagy and inhibits proliferation by regulating miR-328-3p/signal transducer and activator of transcription 3

, 2023
Yi Yang, Yi Nan, Yuhua Du, Shi-Cong Huang, Doudou Lu, Junfei Zhang, Xia Li, Yan Chen, Lei Zhang, Ling Yuan   +9 more
openalex   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

Advanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du, Eun Seo Bae, Thinh T. M. Bui, Seok Beom Lee, Dahan Kim, Jin‐Gyeong Park, Yongjoo Park, Soo Yeon Park, Sangwook Kang, Beomsu Lee, Daniel Shin, Yun Pyo Kang, In‐Gyun Lee, Dae‐Duk Kim, Seokhee Kim, Suckchang Hong, Kyuho Moon, Sang Kook Lee, Dong‐Chan Oh   +18 more
wiley   +1 more source