Results 241 to 250 of about 5,337,491 (425)

Mucous Permeable Nanoparticle for Inducing Cuproptosis‐Like Death In Broad‐Spectrum Bacteria for Nebulized Treatment of Acute Pneumonia

open access: yesAdvanced Science, EarlyView.
Copper‐based nanoparticles doped with BSO, and modified with PEG, not only can it increase the retention ability and mucosal penetration ability in the lungs, but also induce cuproptosis‐like death in bacteria and inhibit bacterial TCA cycle. It can also inhibit bacterial quorum sensing, clear biofilms, reduce bacterial virulence, and thus exert ...
Huiqun Hu   +9 more
wiley   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

open access: yesAdvanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang   +16 more
wiley   +1 more source

Burden of Gastric Cancer.

open access: yesClinical Gastroenterology and Hepatology, 2020
A. Thrift, H. El‐Serag
semanticscholar   +1 more source

Bimodal In Situ Analyzer for Circular RNA in Extracellular Vesicles Combined with Machine Learning for Accurate Gastric Cancer Detection

open access: yesAdvanced Science, EarlyView.
They developed a bimodal EV‐circRNA in situ analyzer (BEISA) using a DNA rectangular frame‐guided hybridization chain reaction (RF‐HCR) system. By combining ML algorithms and bimodal EV‐circRNA in situ analysis, this platform provides a promising tool for the analysis of gastric cancer‐derived EV‐circRNA, making diagnosis and staging of gastric cancer ...
Yuhang Guo   +11 more
wiley   +1 more source

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng   +8 more
wiley   +1 more source

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