CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
Molecular Cancer, 2020 Ferroptosis is a novel mode of non-apoptotic cell death induced by build-up of toxic lipid peroxides (lipid-ROS) in an iron dependent manner. Cancer-associated fibroblasts (CAFs) support tumor progression and drug resistance by secreting various ...
Haiyang Zhang +17 more
semanticscholar +1 more source
Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez +4 more
wiley +1 more source
Genome expression analysis by suppression subtractive hybridization identified overexpression of Humanin, a target gene in gastric cancer chemoresistance [PDF]
, 2014 Background: In cancer cells, apoptosis is an important mechanism that influences the outcome of chemotherapy and the development of chemoresistance.
Ebrahimifard, F. +5 more
core +1 more source
Cancer Discovery, 2021 Single-cell RNA sequencing analysis of over 200,000 gastric cancer cells forms a comprehensive molecular atlas, identifying novel cell lineages and unique interactions between tumor cells and the surrounding microenvironment.
Vikrant Kumar +23 more
semanticscholar +1 more source
Treatment planning with a 2.5 MV photon beam for radiation therapy
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi +5 more
wiley +1 more source
Differential Proteomic Analysis of Human Saliva using Tandem Mass Tags Quantification for Gastric Cancer Detection. [PDF]
, 2016 Novel biomarkers and non-invasive diagnostic methods are urgently needed for the screening of gastric cancer to reduce its high mortality. We employed quantitative proteomics approach to develop discriminatory biomarker signatures from human saliva for ...
Cao, Cheng-Xi +9 more
core +2 more sources
Global burden of oesophageal and gastric cancer by histology and subsite in 2018
Gut, 2020 Objectives To provide updated estimates of the global burden of oesophageal and gastric cancer by subsite and type. Methods Using data from population-based cancer registries, proportions of oesophageal adenocarcinoma (OAC) and squamous cell carcinoma ...
M. Arnold +3 more
semanticscholar +1 more source
MedComm, 2023 Drug resistance remains the greatest challenge in improving outcomes for cancer patients who receive chemotherapy and targeted therapy. Surmounting evidence suggests that a subpopulation of cancer cells could escape intense selective drug treatment by ...
Xiaohai Song +13 more
doaj +1 more source
Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]
, 2007 Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S. +7 more
core +2 more sources
Global Incidence and Mortality of Gastric Cancer, 1980-2018
JAMA Network Open, 2021 Key Points Question Is the global burden of gastric cancer increasing in younger adults compared with older adults? Findings In this cohort study of data from 1980 to 2018 covering more than 1 million cases of gastric cancer, an increasing incidence of ...
M. Wong +7 more
semanticscholar +1 more source