Results 61 to 70 of about 55,714 (331)
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang+4 more
wiley +1 more source
Gastric emptying of liquids in rats dehydrated by water deprivation
The gastric emptying of liquids was investigated in male Wistar rats (8 to 10 weeks old, 210-300 g) dehydrated by water deprivation. In this model of dehydration, weight loss, hematocrit and plasma density were significantly higher in the dehydrated ...
E.C.E. Baracat, E.F. Collares
doaj +1 more source
A deep learning model for gastric diffuse-type adenocarcinoma classification in whole slide images [PDF]
Gastric diffuse-type adenocarcinoma represents a disproportionately high percentage of cases of gastric cancers occurring in the young, and its relative incidence seems to be on the rise. Usually it affects the body of the stomach, and presents shorter duration and worse prognosis compared with the differentiated (intestinal) type adenocarcinoma.
arxiv
COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo+15 more
wiley +1 more source
Functional dyspepsia is a clinical syndrome that features abdominal symptoms centered in the upper abdomen without an organic basis. Three possible mechanisms of gastric dysfunction could be related to functional dyspepsia: 1) delayed gastric emptying, 2)
Motoyasu Kusano+7 more
doaj
Dumping syndrome (DS) is common after gastrectomy or gastric bypass surgery, but DS in children has been described almost exclusively as a complication of Nissen fundoplication.
Younglim Kim, Suk-Bae Moon
doaj +1 more source
Abnormal gastric emptying in the obese has been previously suggested. To explore this concept, we studied a group of 77 subjects composed of 46 obese and 31 age-, sex-, and race-matched nonobese individuals. All of the subjects underwent quantitative fluid/solid gastric emptying assays utilizing a dual radionuclide technique. For the solid phase, obese
Richard A. Wright+4 more
openaire +3 more sources
Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair
CircGLIS3(2), a circRNA transiently upregulated in dermal fibroblasts during acute wound healing, is induced by IL‐1α and TGF‐β. Its RNA activates fibroblasts into matrix‐secreting cells, while its encoded protein enhances proliferation. The RNA stabilizes PCOLCE, and the protein interacts with BTF3, collectively accelerating wound repair. Abstract The
Guanglin Niu+20 more
wiley +1 more source
Possible role of serotonin in the gastrokinetic activity of Amorphophallus paeoniifolius tuber
Background: : Amorphophallus paeoniifolius (Dennst.) Nicolson (Araceae) tuber is consumed by various tribes for the treatment of constipation, hemorrhoids, functional dyspepsia and abdominal pain as ethnomedicinal practices.
Yadu Nandan Dey+5 more
doaj
Gongronema Latifolium delays gastric emptying of semi-solid meals in diabetic dogs [PDF]
The aim of the study was to investigate sonographically the effect of Gongronema latifolium on gastric emptying of semi-solid meals in diabetic dogs. Twenty-five alloxan-induced diabetic dogs were randomly allotted into five groups of five dogs each in a
Agwu, KK, Asuzu, IU, Ogbu, SO
core +2 more sources