Results 71 to 80 of about 55,714 (331)

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

Terapêutica cirúrgica da esofagite de refluxo em doentes com pressão do esfincter esofágico inferior normal.

Acta Médica Portuguesa, 1989
In a group of 12 patients with reflux esophagitis resistant to the medical treatment and normal LES pressure, gastric emptying and bile-gastric (B.G.) reflux (HIDA-CCK test) were determined.
F Veiga Fernandes, P M Costa, C Reis, L Mascarenhas, A Carvalhinhos, M L Moura   +5 more
doaj   +1 more source

RMDL: Recalibrated multi-instance deep learning for whole slide gastric image classification [PDF]

, 2020
The whole slide histopathology images (WSIs) play a critical role in gastric cancer diagnosis. However, due to the large scale of WSIs and various sizes of the abnormal area, how to select informative regions and analyze them are quite challenging during the automatic diagnosis process.
arxiv   +1 more source

Delayed Gastric Emptying in Patients with Prader Willi Syndrome [PDF]

, 2017
Background: A 15 year old girl with Prader-Willi Syndrome (PWS) died of gastric rupture. Systematic literature research revealed seven case reports of PWS patients with acute gastric dilatation, two had a lethal course. The objective of this study was to
Arenz, T., Koletzko, S., Pfluger, Th, Schmidt, H., Schwarzer, A.   +4 more
core  

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Delayed gastric emptying and reduced postprandial small bowel water content of equicaloric whole meal bread versus rice meals in healthy subjects: novel MRI insights [PDF]

, 2013
BACKGROUND/OBJECTIVES: Postprandial bloating is a common symptom in patients with functional gastrointestinal (GI) diseases. Whole meal bread (WMB) often aggravates such symptoms though the mechanisms are unclear. We used magnetic resonance imaging (MRI)
A Accarino, A Langlois, A McIntyre, A Steingoetter, C Costigan, C Hellier-Woods, C L Hoad, CL Hoad, CM Courtin, CY Francis, GF Longstreth, H Fruehauf, HN Johansen, J Serra, J Snook, J Tack, JH Meyer, JM Hebden, JM Kellum, JN Hunt, K Gebruers, L Marciani, L Marciani, L Marciani, L Marciani, L Marciani, MA Kwiatek, N Mathlouthi, P A Gowland, PJ Collins, R C Spiller, R Vincent, RC Hoseney, S E Pritchard, S Shobana   +34 more
core   +2 more sources

Surgical Intervention and Prognosis of Intraductal Papillary Mucinous Adenoma in Elderly Patients: A Single Center Retrospective Study

AGING MEDICINE, EarlyView.
ABSTRACT Objective The incidence of intraductal papillary mucinous neoplasm (IPMN) is rising among elderly patients. This study aims to investigate the clinical features of IPMN in elderly patients (≥ 60 years), analyze risk factors for high‐grade dysplasia (HGD) and invasive cancer (IC), and provide treatment recommendations for elderly patients with ...
Tianhan Sun, Meilan Liu, Qing Wang, Boyue Jiang, Tong Li, Jianfu Cao, Jinghai Song, Jingyong Xu, Hongyuan Cui   +8 more
wiley   +1 more source

Dual Role of Mosapride Citrate Hydrate on the Gastric Emptying Evaluated by the Breath Test in Conscious Rats

Journal of Pharmacological Sciences, 2013
.: Mosapride citrate hydrate (mosapride) has been known to act as a 5-HT4 agonist and to enhance gastric emptying. However, its mode of action, such as time course and dosage effect, on gastric emptying has not been clarified. This study aimed to clarify
Masayuki Uchida, Shigeru Yamato, Kimiko Shimizu, Tomofumi Amano, Hajime Ariga   +4 more
doaj  

The Role of Pyloromyotomy on Gastric Drainage in Esophagectomy and Gastric Pull-up Procedures: A Randomized Clinical Trial Study [PDF]

Journal of Cardio-Thoracic Medicine, 2015
Introduction: Gastric drainage disorder is one of the complications of gastric pull-up and esophagectomy after surgery which might lead to esophageal cancer and benign strictures.
Mohsen Sokouti, Sina Zarrintan, Ziaeddin Rasihashemi, Babak Abri-Aghdam, Esmail Qara-Papaque, Hananeh Orangpour   +5 more
doaj  

Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn’s disease

BMC Gastroenterology, 2012
Background Patients with Crohn’s disease (CD) have been shown to present dyspeptic symptoms more frequently than the general population. Some of these symptoms could be related to motility disorders to some degree. Then, we propose to investigate whether
Nóbrega Ana Carolina Mello, Ferreira Bruno Roberto Silva, Oliveira Graciela Josué, Sales Kamila Maria Oliveira, Santos Armênio Aguiar, Nobre e Souza Miguel Ângelo, Braga Lúcia Libanês Bessa Campelo, Troncon Luiz Ernesto de Almeida, Souza Marcellus Henrique Loiola Ponte   +8 more
doaj   +1 more source