Results 131 to 140 of about 725,921 (266)
ABSTRACT Introduction Pregnancy concurrent with incretin‐based medications is contraindicated due to unknown risk of teratogenicity, as is breastfeeding. The aim of this systematic scoping review was to investigate potential risks and benefits of incretin‐based medications in relation to preconception, pregnancy, and postnatal health, and to propose ...
Kate Maslin +19 more
wiley +1 more source
Rethinking Global Obesity Guidelines: Integrating Evidence, Equity and Precision (2014–2026)
Challenges and evidence in obesity guidelines. ABSTRACT Obesity remains a global health crisis characterized by substantial heterogeneity in diagnosis, management, and policy implementation. Although numerous national and international clinical practice guidelines have been published over the past decade, their translation into evidence‐based and ...
Rosero‐Revelo Ricardo +13 more
wiley +1 more source
Role of gastric inhibitory polypeptide in postprandial hyperinsulinemia of obesity
To assess the contribution of gastric inhibitory polypeptide (GIP) to the postprandial hyperinsulinemia of obesity, secretion rates of GIP (generated from kinetic analyses from infusions of porcine GIP) and insulin (from C-peptide applied to a validated
L. R. Roust +5 more
core +1 more source
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati +12 more
wiley +1 more source
Previous studies on the isolated perfused stomach have shown that gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1(7–36) amide (GLP-1(7–36) amide) stimulate release of somatostatin (somatostatin-like immunoreactivity, SLI).
C. H. S. McIntosh +4 more
core +1 more source
ABSTRACT Background Obesity's global rise has outpaced the effectiveness of “one‐size‐fits‐all” prevention and treatment strategies. The promise of precision medicine lies in addressing the etiological and biological diversity of obesity and transforming it into actionable endotypes.
Nadia Abu Samra +13 more
wiley +1 more source
Background The gut microbiota controls broad aspects of human metabolism and feeding behavior, but the basis for this control remains largely unclear. Given the key role of human dipeptidyl peptidase 4 (DPP4) in host metabolism, we investigate whether ...
Marta Olivares +5 more
doaj +1 more source
Radioimmunoassay of Gastric Inhibitory Polypeptide in Plasma
J, Wishart, H A, Morris, M, Horowitz
openaire +2 more sources
Gastric inhibitory polypeptide and hyperinsulinemia in the Zucker (fa/fa) rat
The role of the gut hormone GIP (gastric inhibitory polypeptide; glucose-dependent insulinotropic polypeptide) in the development of hyperinsulinemia of pre-obese (fa/fa) Zucker rats was investigated.
core

