Results 51 to 60 of about 18,988 (214)

Pathology of Gastric Intestinal Metaplasia: Clinical Implications [PDF]

American Journal of Gastroenterology, 2010
Intestinal metaplasia (IM) of the gastric mucosa is a relatively frequent precancerous lesion (1). The inclusion of IM in a gastric biopsy pathology report often creates uncertainty for the gastroenterologist about the appropriate management. Although the risk of gastric cancer is increased in the presence of IM, the overall risk of gastric cancer in a
Pelayo, Correa, M Blanca, Piazuelo, Keith T, Wilson   +2 more
openaire   +2 more sources

Longitudinal Changes in the Serum Pepsinogen I/II Ratio With Progression of Gastric Atrophy

Journal of Clinical Laboratory Analysis, EarlyView.
Serum pepsinogen (PG) I/II ratio decreased with progression of gastric mucosal atrophy and showed consistent intra‐individual changes over time. In a large cohort with repeated endoscopic evaluations, longitudinal declines in the PG I/II ratio paralleled worsening atrophic stages.
Soie Chung, Jung Kim, Ji Hyun Song, Jooyoung Lee, Sun Young Yang, Eun Young Song   +5 more
wiley   +1 more source

Expression profile of mucins (MUC2, MUC5AC and MUC6) in Helicobacter pylori infected pre-neoplastic and neoplastic human gastric epithelium

Molecular Cancer, 2006
Background Helicobacter pylori (H. pylori) causes gastritis and intestinal metaplasia (IM) that may evolve to gastric carcinoma. The objective of this study was to compare the profile of mucins in the progressive stages of H.
Reis Celso A, Devaraj Niranjali, Jayanthi Venkataraman, Babu Subramani, Devaraj Halagowder   +4 more
doaj   +1 more source

High prevalence of ultra‐short celiac disease in children with low anti‐tissue transglutaminase immunoglobulin A levels: The risk of misdiagnosis without bulb biopsy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite recent advances in diagnostics, celiac disease (CD) diagnosis remains challenging. Ultra‐short celiac disease (USCD) has been proposed as a distinct phenotype characterized by villous atrophy confined to the duodenal bulb, positive celiac serology, and clinical features consistent with CD.
Antonio Pizzol, Eleonora Saraceno, Anna Opramolla, Laura Giugliano, Cristina Chiadò, Tilde Manetta, Gabriella Canavese, Enrico Falco, Michele Pinon, Pier Luigi Calvo   +9 more
wiley   +1 more source

Prevalence of barrett's esophagus, its relationship with chronic Helicobacter pylori-associated gastritis, atrophy and metaplasia of gastric mucosa

Клінічна та профілактична медицина, 2019
The aim - to identify the frequency of Helicobacter pylori infection, atrophic and metaplastic changes in the gastric mucosa in patients with Barrett's esophagus. Materials and methods.
T.V. Serha, O.G. Kuryk, V.A. Yakovenko, G.A. Solovyova, R.P. Tkachenko   +4 more
doaj   +1 more source

Xanthomas and precancerous changes of the stomach: an accidental combination or an important prognostic endoscopic marker?

Gastroenterologìa, 2023
Background. The article deals with the study of gastric xanthomas, benign accidental formations with an unknown etiopathogenesis, which, according to the literature, are associated with a number of pathological conditions (atrophic gastritis, intestinal ...
O.V. Simonova, L.M. Mosiychuk, O.P. Petishko   +2 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer

Med Research, EarlyView.
ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang, Chenchen Wang, Tianliang Liu, Ziliang Wang, Zhe Zhang   +4 more
wiley   +1 more source

Murine Models of Gastric Corpus PreneoplasiaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2017
Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of
Christine P. Petersen, Jason C. Mills, James R. Goldenring   +2 more
doaj   +1 more source

Structural and functional state of the thyroid gland in patients with precancerous conditions of the stomach

Gastroenterologìa, 2020
Background. The mechanisms of the functional interaction of the stomach and thyroid gland are based on the biological action of thyroid hormones. According to the European guidelines MAPS II, precancerous conditions of the stomach include atrophy and ...
L.М. Mosiychuk, I.S. Konenko, O.M. Tatarchuk, O.P. Petishko, О.V. Simonova, E.N. Shevtsova   +5 more
doaj   +1 more source