Results 61 to 70 of about 18,988 (214)
VIEW, EarlyView.We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
Apoptosis and proliferation in Helicobacter pylori-associated gastric intestinal metaplasia
, 2001 Background: Imbalance between apoptosis and proliferation may be one of the mechanisms underlying H. pylori associated gastric carcinogenesis. Aim: To examine the cell kinetics of gastric intestinal metaplasia and the effect of H.
Go, MYY +6 more
core +1 more source
Arquivos de Gastroenterologia, 2012 CONTEXT: The prevalence of obesity has been increasing in modern society. Roux-en-y gastric bypass is a bariatric surgery that involves the exclusion of significant part of the stomach.
Judite Dietz +3 more
doaj +1 more source
Intestinal Metaplasia and Gastric Carcinoma [PDF]
, 1990 Previous studies have suggested that gastric carcinogenesis is a multistage process involving first gastritis, then intestinal metaplasia, dysplasia of increasing severity and finally carcinoma. The exact role of intestinal metaplasia in the histogenesis
Aitchison, Michael
core
Prevalence of High-Risk Groups for Gastric Carcinoma – A Biopsy Finding
Nepalese Medical Journal, 2018 Introduction: Gastric carcinoma is leading cause of death world wide including Nepal. The 5 years survival rate of gastric carcinoma (25%) has drastically decreased compared to early gastric cancers (90-90%) hence implying the need for early detection ...
Geetika KC +2 more
doaj +1 more source
Journal of Infection in Developing Countries, 2021 Introduction: Helicobacter pylori infection is the major risk factor of atrophic gastritis and intestinal metaplasia. The vacA gene is one of the most virulence factors of H.
Mohamed Reda Jouimyi +9 more
doaj +1 more source
Cancer Science, EarlyView.DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley +1 more source
Histopathology, EarlyView.GBASCs are MMRp tumours, exhibiting minimal HER2 overexpression and elevated PD‐L1 expression compared to adenocarcinomas. Especially in metastatic and TP53‐wild type tumours, GBASCs can express CLDN18, albeit limited to the glandular component. Their genomic profile resembles that of adenocarcinomas with an enrichment in alterations on PIK3CA, PTEN ...
Jessica Gasparello +20 more
wiley +1 more source
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, EarlyView.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
, 2018 Aim: Carcinomas of the stomach are a heterogeneous group of lesions in terms of architecture, pattern of growth, cell differentiation, and histogenesis.
Irfan Ansari +7 more
core +1 more source