Targeting the YAP-BST2 Axis Overcomes Intrinsic Anti-PD-1 Resistance in Metastatic Gastric Cancer. [PDF]
Adv Sci (Weinh)Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Zhang W +17 more
europepmc +2 more sources
Korean Gastric Cancer Association- Led Nationwide Survey on Surgically Treated Gastric Cancers in 2019 [PDF]
, 2021 Purpose: The Korean Gastric Cancer Association (KGCA) has been conducting nationwide surveys on patients with surgically treated gastric cancer, every 5 years, since 1995. This study details the results of the survey conducted in 2019.
권인규
core +1 more source
Journal of the Formosan Medical Association, 2020 Atrophic glossitis (AG) is characterized by the partial or complete absence of filiform papillae on the dorsal surface of the tongue. AG may reflect the significant deficiencies of some major nutrients including riboflavin, niacin, pyridoxine, vitamin ...
Chun-Pin Chiang +5 more
doaj +1 more source
Early-Life Nutritional Disruption Reshapes Gastric Epithelial Development Through Coordinated Changes in the Dynamics and Signaling of Proliferative Niches. [PDF]
J Cell PhysiolABSTRACT Gastric gland cells originate from two proliferative niches: the main rapid one in the isthmus, and the slow secondary one in the base. However, while nutrition is dependent on breastfeeding, the proliferative niches are not established, and proliferation occurs along the gland. Currently, we investigated the influence of early weaning (EW) on
Rattes IC +3 more
europepmc +2 more sources
Autoimmune gastritis associated diseases: report of 3 cases and literature review [PDF]
Zhenduanxue lilun yu shijian, 2021 Objective: To analyze the clinical characteristics of autoimmune gastritis associated diseases, and review the related literatures so as to provide reference for clinical practice.
TAN Yingbing, XIE Lin, WU Yunling, CHEN Ping
doaj +1 more source
Parietal cell distribution informs gastric bypass procedure [PDF]
, 2023 INTRODUCTION: Roux-en-Y Gastric Bypass (RYGB) is a common bariatric procedure that facilitates weight loss and reduces co-morbidities of obesity. A common complication is marginal ulceration, caused by an overproduction of hydrochloric acid from the ...
Rukavina, Nadia A.
core +1 more source
The prevalence and significance of circulating antibodies to gastric intrinsic factor and parietal cells in gastric carcinoma [PDF]
Gut, 1971 The prevalence of circulating antibodies to gastric intrinsic factor and parietal cells was examined in 60 patients with histologically proven gastric carcinoma and was found not to differ from the prevalence of these antibodies in control subjects of similar age and sex distribution.
B, Ungar, R G, Strickland, C M, Francis
openaire +2 more sources
Helicobacter pylori cag-Pathogenicity island-dependent early immunological response triggers later precancerous gastric changes in Mongolian gerbils [PDF]
, 2009 Infection with Helicobacter pylori, carrying a functional cag type IV secretion system (cag-T4SS) to inject the Cytotoxin associated antigen (CagA) into gastric cells, is associated with an increased risk for severe gastric diseases in humans.
Haas, Rainer +13 more
core +2 more sources
Journal of the Formosan Medical Association, 2019 Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal diseases characterized by recurrent and painful ulcerations on the movable or nonkeratinized oral mucosae.
Chun-Pin Chiang +5 more
doaj +1 more source
Gastric parietal cell and thyroid autoantibodies in patients with burning mouth syndrome
Journal of the Formosan Medical Association, 2020 Background/Purpose: Gastric parietal cell antibody (GPCA), thyroglobulin antibody (TGA), and thyroid microsomal antibody (TMA) are organ-specific autoantibodies.
Chun-Pin Chiang +5 more
doaj +1 more source