Results 111 to 120 of about 3,866,464 (201)

JBM834235_SUPPLEMENT_MATERIAL_CLN – Supplemental material for New and old biomarkers in the differential diagnosis of lung cancer: Pro-gastrin-releasing peptide in comparison with neuron-specific enolase, carcinoembryonic antigen, and CYFRA 21-1

open access: yes, 2019
Supplemental material, JBM834235_SUPPLEMENT_MATERIAL_CLN for New and old biomarkers in the differential diagnosis of lung cancer: Pro-gastrin-releasing peptide in comparison with neuron-specific enolase, carcinoembryonic antigen, and CYFRA 21-1 by ...
Lorenzo Spaggiari (4813800)   +6 more
core   +1 more source

Highly improved metabolic stability and pharmacokinetics of indium-111-DOTA-gastrin conjugates for targeting of the gastrin receptor

open access: yes, 2011
The development of metabolically stable radiolabeled gastrin analogues with suitable pharmacokinetics is a topic of recent research activity. These imaging vectors are of interest because the gastrin/CCK2 receptor is highly overexpressed in different ...
Tanja Gmeiner-Stopar   +23 more
core   +1 more source

Gastric Peptides-Gastrin and Somatostatin

open access: yes, 2019
Gastric acid secretion (i) facilitates digestion of protein as well as absorption of micronutrients and certain medications, (ii) kills ingested microorganisms, including Helicobacter pylori, and (iii) prevents bacterial overgrowth and enteric infection.
Jens F. Rehfeld   +3 more
core   +1 more source

Metabolism and influence of gastrin-52 on gastric acid secretion in humans

open access: yes, 1995
It has been shown recently that the two largest alpha-carboxyamidated progastrin products are gastrin-71 and gastrin-52. Human gastrin-52 has now been synthesized, and the effect on gastric acid secretion and elimination from plasma was examined and ...
C. P. Hansen, F. Stadil, J. F. Rehfeld
core   +1 more source

Gastrin is not a physiological regulator of pancreatic exocrine secretion in the dog

open access: yes, 1987
The role of gastrin as a regulator of exocrine pancreatic secretion has not been proven adequately. In the present study we therefore compared the relative molar potencies of sulfated and unsulfated gastrin 17 with structurally related CCK peptides ...
K. Gyr   +4 more
core   +1 more source

Gastrin mediates the gastric mucosal proliferative response to feeding

open access: yes, 1996
The role of endogenous gastrin in oxyntic mucosal proliferation during feeding in the rat was studied by immunoneutralization with a gastrin-specific monoclonal antibody (MAb) (CURE 051091.5).
K. C. Lloyd   +3 more
core   +1 more source

Gastrin-induced apoptosis contributes to carcinogenesis in the stomach

open access: yes, 2009
Hypergastrinemia in INS-GAS mice leads to accelerated carcinogenesis of the stomach, but the mechanisms have not been well defined. We investigated the possible role of gastrin-induced gastric cell apoptosis in the development of gastric cancer.
Betz, Kelly S.   +8 more
core   +1 more source

Pharmacokinetics and organ specific metabolism of glycine-extended and amidated gastrin in sheep

open access: yes, 1992
Glycine (Gly)-extended gastrin has been described as the inactive precursor form of the biologically active amidated gastrin. The ratio of Gly-extended to amidated gastrin is higher in the circulation than in tissue, suggesting either differential ...
G. D. Ciccotosto, A. Shulkes
core   +1 more source

Metabolism and acid secretory effect of sulfated and nonsulfated gastrin-6 in humans

open access: yes, 2000
The antral hormone gastrin is synthesized by processing progastrin into different peptides that stimulate gastric secretion. The effect on acid secretion depends mainly on the metabolic clearance rate of the peptides, but some of them may differ in ...
C. Palnæs Hansen   +2 more
core   +1 more source

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