Results 121 to 130 of about 65,820 (233)

Evaluation of Gastric pH and Gastrin Concentrations in Horses Subjected to General Inhalation Anesthesia in Dorsal Recumbency

open access: yesAnimals
The prevalence of gastric disorders in high-performance horses, especially gastric ulceration, ranges from 50 to 90%. These pathological conditions have negative impacts on athletic performance and health.
Jesus Leonardo Suarez Guerrero   +8 more
doaj   +1 more source

Gastrin promotes calcitonin secretion, gene activation, and proliferation in human C-cells [PDF]

open access: bronze, 2003
Michael Blaeker   +5 more
openalex   +1 more source

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li   +5 more
wiley   +1 more source

Effects of rabeprazole, 20 mg, or esomeprazole, 20 mg, on 24‐h intragastric pH and serum gastrin in healthy subjects [PDF]

open access: bronze, 2002
Steve Warrington   +5 more
openalex   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

open access: yesThe Prostate, Volume 86, Issue 1, Page 65-83, January 2026.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard   +17 more
wiley   +1 more source

A Mechanism‐Based Multi‐Level Population PK/PD Model for Potassium‐Competitive Acid Blockers

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
Schematic overview of a mechanism‐based, multi‐level population model for potassium‐competitive acid blockers. ABSTRACT Potassium‐competitive acid blockers (PCABs) are emerging alternatives to proton pump inhibitors for the treatment of acid‐related diseases.
Woojin Jung   +6 more
wiley   +1 more source

Diagnostic significance of plasma gastrin concentration for the diagnosis of type 1 abomasal ulcer in water buffalo: A preliminary case control study

open access: yesBulgarian Journal of Veterinary Medicine
The type 1 abomasal ulcer (AU1) does not have specific clinical signs, so there is a need to identify some early biochemical markers for its diagnosis in cattle and buffaloes.
S. A. Hussain, S. K. Uppal , N. K. Sood
doaj   +1 more source

A Case of IgG4‐Related Disease That Mimics an Anterior Mediastinal Malignant Tumour

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We describe a rare case of IgG4‐related disease presenting as an anterior mediastinal mass mimicking malignancy. This case demonstrates the importance of considering IgG4‐related disease in the differential diagnosis of mediastinal tumours, even when FDG‐PET shows abnormal accumulation and serum IgG4 levels are not particularly high.
Noriaki Nishimura   +12 more
wiley   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

open access: yesSmall Methods, Volume 10, Issue 2, 22 January 2026.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai   +9 more
wiley   +1 more source

Oral tolerogenic vaccine combined with gastrin restores immune tolerance and beta-cell function in NOD mice with Type 1 diabetes

open access: yesFrontiers in Immunology
Background and objectiveType 1 diabetes (T1D) results from autoimmune destruction of pancreatic β-cells. Current therapies fail to address the multiple mechanisms driving disease progression.
Jacob Cobb   +4 more
doaj   +1 more source

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