Results 71 to 80 of about 5,629 (238)

E‐selectin affinity glycoproteomics reveals neuroendocrine proteins and the secretin receptor as a poor‐prognosis signature in colorectal cancer

open access: yesMolecular Oncology, Volume 19, Issue 3, Page 635-658, March 2025.
Screening colorectal tumors for glycoproteins linked to disease progression has revealed several potential therapeutic targets. The secretin receptor (SCTR), identified as a marker of poor prognosis and metastasis in colorectal cancer, has been shown to be a key carrier of N‐glycans with sialylated Lewis antigens. These cancer‐specific glycoproteoforms
Sofia Cotton   +12 more
wiley   +1 more source

Sporadic duodenal macrogastrinoma: a rare case report

open access: yesActa Medica Lituanica, 2013
Gastrinomas are rare neuroendocrine tumors characterized by the secretion of gastrin, which causes hyperchlorhydria, thereby producing the Zollinger-Ellison syndrome. In most cases this syndrome manifests as severe peptic ulcer disease. We are presenting
Dainius Šimčikas   +5 more
doaj   +1 more source

Hormonal crises following receptor radionuclide therapy with the radiolabeled somatostatin analogue [177Lu-DOTA0,Tyr 3]octreotate [PDF]

open access: yes, 2008
Introduction: Receptor radionuclide therapy is a promising treatment modality for patients with neuroendocrine tumors for whom alternative treatments are limited.
Aken, M.O. (Maarten) van   +7 more
core   +1 more source

GASTRINOMAS Clinical syndromes [PDF]

open access: yesActa Oncologica, 1989
During the last 17 years about 100 gastrinomas have been diagnosed in Denmark. With background of the Danish material and the literature the clinical features and pathology of gastrinoma are reviewed and its medical and surgical treatment discussed.
openaire   +2 more sources

Endoscopic ultrasound‐guided tissue acquisition allows a reliable proliferation assessment of small (≤20 mm) pancreatic neuroendocrine tumors

open access: yesAnnals of Gastroenterological Surgery, Volume 9, Issue 2, Page 339-346, March 2025.
Distribution of Ki‐67 proliferation indices in EUS‐TA versus surgical histological assessment. Abstract Aim Evidence regarding the reliability of endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) for assessing histological proliferation and WHO grading of small (≤20 mm) pancreatic neuroendocrine tumors (PanNETs) is limited.
Yoshihide Nanno   +9 more
wiley   +1 more source

Resection of Gastrinomas

open access: yesAnnals of Surgery, 1983
Exploratory laparotomy and a search for gastrinomas was performed in 52 patients with the Zollinger-Ellison syndrome (ZES). Gastrinoma tissue was resected in 11 patients (21%), 6 (12%) of whom appear to have been cured. After surgery, serum gastrin levels in these six patients have remained normal from 10 months to 10 years.
C W, Deveney   +5 more
openaire   +3 more sources

Calcium sensing receptor expression is downregulated in gastroenteropancreatic neuroendocrine tumours via epigenetic mechanisms

open access: yesInternational Journal of Cancer, Volume 156, Issue 5, Page 980-992, 1 March 2025.
What's New? Epigenetic regulation has been suggested to play a major role in the pathogenesis of gastroenteropancreatic neuroendocrine tumours, but the underlying mechanisms remain poorly understood. Here, the authors show in two independent cohorts that the calcium‐sensing receptor (CaSR) is down‐regulated in gastroenteropancreatic neuroendocrine ...
Katherine A. English   +15 more
wiley   +1 more source

Case report: optimal tumor cytoreduction and octreotide with durable disease control in a patient with MEN-1 and Zollinger-Ellison syndrome—over a decade of follow-up

open access: yesWorld Journal of Surgical Oncology, 2019
Background Zollinger-Ellison syndrome (ZES) is a rare condition characterized by hypersecretion of gastrin by gastrinoma tumors leading to severe peptic ulcer disease with potential development of gastric carcinoid tumors.
Lynsey M. Daniels   +6 more
doaj   +1 more source

Zollinger-Ellison syndrome: Revelation of the gastrinoma triangle

open access: yesRadiology Case Reports, 2015
Zollinger-Ellison syndrome is a complex condition in which one or more tumors form in the patient's pancreas or upper duodenum. These tumors, called gastrinomas, secrete excessive amounts of gastrin, and almost all develop ulcers.
Rong-Hsin Yang, MD, Yum-Kung Chu, MD
doaj   +1 more source

Primary hepatic gastrinoma, extremely rare case presentation and its surgical resolution, in a third level hospital in Mexico [PDF]

open access: diamond, 2023
Rogelio González-López   +7 more
openalex   +1 more source

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