Results 71 to 80 of about 1,354,341 (319)

Correlation between postoperative prognosis in gastrointestinal cancer patients and blastformation rate of lymphocytes [PDF]

open access: yes, 1977
Gastrointestinal cancer patients were followed up for up to 30 months postoperatively and their clinical status related to a parameter of nonspecific immunity, the blastformation rate of peripheral blood lymphocytes against phytohemagglutinin.
Orita, Kunzo, Miwa, Hiroaki
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

An Unusual Complication of Congenital Diaphragmatic Hernia

open access: yesEuropean Journal of Pediatric Surgery Reports, 2017
A term newborn was referred to our unit with a postnatal diagnosis of a right-sided congenital diaphragmatic hernia (CDH). She was managed with high-frequency oscillatory ventilation, inotropic support, and nitric oxide, with planned surgical repair when
E Tian Tan, Keren Sloan, Kokila Lakhoo
doaj   +1 more source

Ewing's Sarcoma of the Gastrointestinal Tract—A Case Series

open access: yesAsian Journal of Oncology, 2022
Ewing's sarcoma is a neoplasm of the undifferentiated small round cells, which generally affects the bone and deep soft tissues of children and adolescents. Extraskeletal Ewing's sarcomas are less common than skeletal Ewing's sarcoma with the most common
Prakash Purushothaman   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Intensive care management of upper gastrointestinal bleeding in children: A review

open access: yesJournal of Pediatric Critical Care, 2016
Managing children having an upper gastrointestinal bleed (UGIB) can be anxiety-provoking for an intensivist, as the differential diagnosis can vary from a benign disorder to a life-threatening condition, with the potential for high fatality if the ...
Veena Raghunathan   +3 more
doaj   +1 more source

Immediate effects of acute Mars mission equivalent doses of SEP and GCR radiation on the murine gastrointestinal system-protective effects of curcumin-loaded nanolipoprotein particles (cNLPs)

open access: yesFrontiers in Astronomy and Space Sciences, 2023
Introduction: Missions beyond low Earth orbit (LEO) will expose astronauts to ionizing radiation (IR) in the form of solar energetic particles (SEP) and galactic cosmic rays (GCR) including high atomic number and energy (HZE) nuclei. The gastrointestinal
Jonathan Diaz   +14 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Catastrophic Gastrointestinal Manifestations of Post-Transplant Lymphoproliferative Disorder [PDF]

open access: yes, 2011
Post-transplant lymphoproliferative disorder is a rare complication after bone marrow transplantation and frequently involves gastrointestinal tract, but the endoscopic characteristics and catastrophic clinical manifestations in adults have not been ...
HSU, YAO-CHUN;LIAO, WEI-CHIH;WANG, HSIU-PO;YAO, MING;LIN, JAW-TOWN   +1 more
core   +1 more source

Saliva RNA Biomarkers of Gastrointestinal Dysfunction in Children With Autism and Neurodevelopmental Disorders: Potential Implications for Precision Medicine

open access: yesFrontiers in Psychiatry, 2022
Gastrointestinal (GI) disorders are common in children with neurodevelopmental disorders such as autism spectrum disorder (ASD). A limited understanding of the biologic factors that predispose this population to GI disorders has prevented development of ...
David Q. Beversdorf   +9 more
doaj   +1 more source

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