Results 51 to 60 of about 4,823,404 (316)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Stratification of gastric cancer risk using a deep neural network

JGH Open, 2020
Background and Aim Stratifying gastric cancer (GC) risk and endoscopy findings in high‐risk individuals may provide effective surveillance for GC.
Hiroko Nakahira, Ryu Ishihara, Kazuharu Aoyama, Mitsuhiro Kono, Hiromu Fukuda, Yusaku Shimamoto, Kentaro Nakagawa, Masayasu Ohmori, Taro Iwatsubo, Hiroyoshi Iwagami, Kenshi Matsuno, Shuntaro Inoue, Noriko Matsuura, Satoki Shichijo, Akira Maekawa, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi, Koji Higashino, Noriya Uedo, Takashi Matsunaga, Tomohiro Tada   +21 more
doaj   +1 more source

Acromegaly and gastrointestinal cancer [PDF]

Cancer, 1991
A cohort of 1041 men who were discharged from the hospital with a diagnosis of acromegaly were examined for subsequent cancer. With a mean follow-up time of 8.3 years, an increased rate of cancers of the digestive organs was observed (27 cases; standard incidence ratio [SIR], 2.0; 95% confidence interval [CI], 1.3 to 2.9).
E, Ron, G, Gridley, Z, Hrubec, W, Page, S, Arora, J F, Fraumeni   +5 more
openaire   +2 more sources

Overall Volume Trends in Esophageal Cancer Surgery Results From the Dutch Upper Gastrointestinal Cancer Audit [PDF]

, 2021
OBJECTIVE: In the pursuit of quality improvement, this study aimed to investigate volume-outcome trends in oncologic esophagectomy in the Netherlands. SUMMARY OF BACKGROUND DATA: Concentration of Dutch esophageal cancer care was dictated by introducing ...
Dutch Upper Gastrointestinal Cancer Audit (DUCA) Group, MS CGO, Cancer   +2 more
core  

Upper Gastrointestinal Cancer and Liver Cirrhosis

, 2022
SIMPLE SUMMARY: There is a higher incidence rate of upper gastrointestinal cancer in those with liver cirrhosis. The contributing factors include gastric ulcers, congestive gastropathy, zinc deficiency, alcohol drinking, tobacco use and gut microbiota ...
Chiung-Fang Chang, Chang, Chiung-Fang, Jeng, Chi-Juei, Kuo-Shyang Jeng, Chi-Juei Jeng, Chih-Hsuan Wang, Wang, Chih-Hsuan, Jeng, Kuo-Shyang, Sheen, I-Shyan, I-Shyan Sheen   +9 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

MTUS1 is a promising diagnostic and prognostic biomarker for colorectal cancer

World Journal of Surgical Oncology, 2022
Background The morbidity and mortality of colorectal cancer (CRC) remain high, posing a serious threat to human life and health. The early diagnosis and prognostic evaluation of CRC are two major challenges in clinical practice.
Lin-Yao Cheng, Mao-sen Huang, Hua-Ge Zhong, Hai-Ming Ru, Si-Si Mo, Chun-Yin Wei, Zi-Jie Su, Xian-Wei Mo, Lin-Hai Yan, Wei-Zhong Tang   +9 more
doaj   +1 more source

Gastrointestinal Cancer Metastasis [PDF]

Gastroenterology Research and Practice, 2012
It is well acknowledged that the poor prognosis of gastrointestinal cancer is largely due to metastasis, which is the biological hallmark of malignant tumors. Metastasis is considered to be a multistep process in which malignant tumor cells spread inconsecutively from original site to distant organs. As for cancers of gastrointestinal tract, the common
Jin-Lian Chen, Richard Ricachenevsky Gurski, Keiichi Takahashi, Roland Andersson   +3 more
openaire   +3 more sources

Cancer Trends: Soft Tissue Sarcomas [PDF]

, 2014
Sarcomas are a group of uncommon cancers that originate from mesenchymal cells as opposed to more well-known cancers that develop from epithelial tissue.
National Cancer Registry Ireland (NCRI)
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source