Results 81 to 90 of about 4,823,404 (316)

Therapeutic actions of melatonin on gastrointestinal cancer development and progression.

, 2013
Melatonin exerts a multitude of physiological functions including the regulation of the sleep cycle and circadian rhythm. Although the synthesis of melatonin in the pineal gland is regulated by changes in the light/dark cycle, the release of melatonin in
K. Mcdaniel, G. Alpini, F. Meng, K. Jensen, J. Venter, R. Glenister, H. Francis, GAUDIO, EUGENIO, S. Glaser, G. Dusio   +9 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

UPPER GASTROINTESTINAL CANCER IN ARDABIL,NORTH-WEST OF IRAN: A REVIEW [PDF]

Introduction: Cancer is a serious health problem worldwide, imposing a large economical and psychological burden as well as loss of life and productivity.1 Lots of effort and money have been put in the fields of clinical, epidemiological, pharmacological,
ملک زاده, رضا, ناصری مقدم, سیاوش, یزدانبد, عباس   +2 more
core   +1 more source

Circulating MicroRNAs in Gastrointestinal Cancer

, 2021
Gastrointestinal cancer (GIC) is a common disease and is considered to be the leading cause of cancer-related death worldwide; thus, new diagnostic and therapeutic strategies for GIC are urgently required. Noncoding RNAs (ncRNAs) are functional RNAs that
Mitsunobu Imasato, Hiroki Akamatsu, Manabu Mikamori, Tadafumi Asaoka, Kenta Furukawa, Jeongho Moon, Hirofumi Yamamoto, Kentaro Kishi, Yujiro Nakahara, Kazuya Iwamoto, Tsunekazu Mizushima, Masahisa Ohtsuka, Awad Shamma, Atsushi Naito, Satoshi Hyuga   +14 more
core   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Childhood, adolescent and young adult cancer: cancer trends report

, 2023
This is the third Cancer Trends Report the National Cancer Registry Ireland (NCRI) has published on childhood cancers and the first to include cancers in adolescents and young adults (AYA) (up to 24 years of age).
National Cancer Registry Ireland (NCRI)
core  

Early-Onset Cancer in the Gastrointestinal Tract Is on the Rise-Evidence and Implications

, 2023
Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in younger populations in the past three decades. Moreover, recent evidence also demonstrates a similar trend in gastric, pancreatic, and biliary tract cancers.
Ben-Aharon, I, van, Laarhoven HWM, Lordick, F, Obermannova, R, Fontana, E, Nilsson, M,, Magnus Nilsson, Irit Ben-Aharon, Elisa Fontana, Radka Obermannova, Florian Lordick, Hanneke W.M. van Laarhoven   +11 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Endoscopic landmarks corresponding to anatomical landmarks for esophageal subsite classification

DEN Open
Objectives Individual treatment strategies for esophageal cancer have been investigated based on the anatomical subsite classification. Accurate subsite classification based on these anatomical landmarks is thus important. We investigated the suitability
Ryu Ishihara, Yasuhiro Tani, Yuki Okubo, Yuya Asada, Tomoya Ueda, Daiki Kitagawa, Takehiro Ninomiya, Atsuko Tamashiro, Shunsuke Yoshii, Satoki Shichijo, Takashi Kanesaka, Sachiko Yamamoto, Yoji Takeuchi, Koji Higashino, Noriya Uedo, Tomoki Michida   +15 more
doaj   +1 more source