Results 21 to 30 of about 129,157 (226)

Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]

, 2019
Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R., Ismagilov, Rustem F., Rolando, Justin C.   +2 more
core   +1 more source

The Role of the Microbiome in Gastrointestinal Cancer [PDF]

Gastroenterology Clinics of North America, 2016
Humans are host to complex microbial communities previously termed normal flora and largely overlooked. However, resident microbes contribute to both health and disease. Investigators are beginning to define microbes that contribute to the development of gastrointestinal malignancies and the mechanisms by which this occurs. Resident microbes can induce
Lydia E. Wroblewski, Lori A. Coburn, Lori A. Coburn, Richard M. Peek   +3 more
openaire   +3 more sources

A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut [PDF]

, 2014
Dietary InsP6 can modulate eukaryotic cell proliferation and has complex nutritive consequences, but its metabolism in the mammalian gastrointestinal tract is poorly understood.
Abrahamse, Ali, Brünger, Caffrey, Chakraborty, Chi, Cho, Ciccarelli, Craxton, Dionisio, Ellis, Fallingborg, Fox, Haefner, Haros, Keeling, Konietzny, Kostrewa, Kumar, Landau, Michell, Nogimori, Oakley, Osborn, Patrick, Prasad, Rigden, Romano, Shen, Steer, Szijgyarto, Tamayo-Ramos, Tamura, Tremaroli, Vucenik, Whelan, Windhorst, Xu, Yu   +38 more
core   +2 more sources

Antibiotic-induced disruption of the microbiome exacerbates chemotherapy-induced diarrhoea and can be mitigated with autologous faecal microbiota transplantation [PDF]

, 2021
BACKGROUND: Chemotherapy is well documented to disrupt the gut microbiome, leading to poor treatment outcomes and a heightened risk of adverse toxicity. Although strong associations exist between its composition and gastrointestinal toxicity, its causal ...
da Silva Ferreira, Ana R, Harmsen, Hermie J M, Havinga, Rick, Tissing, Wim J E, van der Aa, Stijn A R, Wardill, Hannah R   +5 more
core   +2 more sources

The Gastrointestinal Microbiome and the Enteropathogenetic Syndromes [PDF]

Open Forum Infectious Diseases, 2016
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Anna Lucchini, Giovanni Di Perri, Rossana Cavallo, Roberto Angilletta, Lucina Fossati, Stefania Raviolo, Francesco Giuseppe De Rosa, Silvia Corcione, Claudia Filippini   +8 more
openaire   +3 more sources

Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. [PDF]

, 2019
On December 17, 2018, the North American branch of the International Life Sciences Institute (ILSI North America) convened a workshop "Can We Begin to Define a Healthy Gut Microbiome Through Quantifiable Characteristics?" with >40 invited academic ...
Antonopoulos, Armitage, AVA, Singapore, Azad, Backhed, Barbara O Schneeman, Beaton, Beukers, Bindels, Bindels, Borewicz, Brazilian Health Regulatory Agency (ANVISA), Buddington, Cammarota, Campbell-Lendrum, Cantarel, Caporaso, Carlson, Cindy Davis, Claire M Fraser, Costea, Cummings, Curtis Huttenhower, Damen, Dao, David, David, Davis, Davoren, Desai, Deschasaux, Dethlefsen, De Preter, Earle, EFSA, EFSA, Eloe-Fadrosh, Esaiassen, European Commission, European Commission, Falony, FAO and WHO, FAO and WHO, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA, FDA-NIH Biomarker Working Group, Fedacko, Fei, Ferretti, Fischbach, Flaherman, Flint, Forbes, Foster, Fragiadakis, Francois, François, François, Gibson, Government of Canada, Gregory, Gupta, Hadizadeh, He, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Health Canada, Hermansson, Hildebrand, Ho, Holmes, Holmes, Holscher, Insel, Jacobsen, Jakobsson, Jangi, Janssens, Japan Consumer Affairs Agency, Japan Consumer Affairs Agency, Japan Ministry of Health, Labour, and Welfare, Japan Ministry of Health, Labour, and Welfare, Jens Walter, Jones, Kennedy, Koenig, Korpela, Kristensen, Kristin Verbeke, Kritchevsky, Krumbeck, Lahti, Lam, Langdon, Lawley, La Fata, Leiby, Lim, Lloyd-Price, Lohner, Lozupone, Makki, Maldonado-Gómez, Marcobal, Marie E Latulippe, Martin, Martinez, Martínez, Martínez, Martínez, Matamoros, McBurney, McBurney, McBurney, McFarland, Michael I McBurney, Miller, MOH Malaysia, MOH Malaysia, MOPH Thailand, Mould, Mueller, NDAC, Palleja, Perez-Muñoz, Rattanaprasert, Roager, Robb, Rothschild, Round, Russell, Rutishauser, Saxelin, Schloissnig, Schlomann, Schneeberger, Schroeder, Snijder, Song, Sonnenburg, Sonnenburg, Sprockett, Sundin, Surana, Tanemura, Tannock, Taverniti, The Human Microbiome Project Consortium, Tremlett, Trowell, Vandeputte, Vangay, Vatanen, Vellend, Venkataraman, Venkataraman, Voigt, von Wintzingerode, Walter, Wan, Wang, Watson, Wedekind, Windey, Windey, Windey, Wong, Wu, Yassour   +177 more
core   +1 more source

The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. [PDF]

, 2012
Recent molecular studies have revealed a highly complex bacterial assembly in the canine intestinal tract. There is mounting evidence that microbes play an important role in the pathogenesis of acute and chronic enteropathies of dogs, including ...
Cook, Audrey K., Dillman, Enricka M., Dowd, Scot E., García Mazcorro, José Francisco, Heilmann, Romy M., Heimesaat, Markus M., Ivanov, Ivan, Kachroo, Priyanka, Markel, Melissa, Minamoto, Yasushi, Steiner, Jörg M., Suchodolski, Jan S., Toresson, Linda, Unterer, Stefan   +13 more
core   +9 more sources

Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]

, 2019
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V, Sharpton, Suzanne R, Terrault, Norah A, Yong, Germaine JM   +3 more
core   +1 more source

Visceral Pain and Gastrointestinal Microbiome

Journal of Neurogastroenterology and Motility, 2015
A complex set of interactions between the microbiome, gut and brain modulate responses to visceral pain. These interactions occur at the level of the gastrointestinal mucosa, and via local neural, endocrine or immune activity; as well as by the pro-duction of factors transported through the circulatory system, like bacterial metabolites or hormones ...
Maciej Chichlowski, Colin D. Rudolph
openaire   +4 more sources

Arsenic and the gastrointestinal tract microbiome

Environmental Microbiology Reports, 2020
SummaryArsenic is a toxin, ranking first on the Agency for Toxic Substances and Disease Registry and the Environmental Protection Agency Priority List of Hazardous Substances. Chronic exposure increases the risk of a broad range of human illnesses, most notably cancer; however, there is significant variability in arsenic‐induced disease among exposed ...
Timothy R. McDermott, John F. Stolz, Ronald S. Oremland   +2 more
openaire   +3 more sources