In Vivo Wireless Sensors for Gut Microbiome Redox Monitoring [PDF]
arXiv, 2019 A perturbed gut microbiome has recently been linked with multiple disease processes, yet researchers currently lack tools that can provide in vivo, quantitative, and real-time insight into these processes and associated host-microbe interactions. We propose an in vivo wireless implant for monitoring gastrointestinal tract redox states using oxidation ...
arxiv
The gut microbiota and immune checkpoint inhibitors. [PDF]
, 2018 Although immunotherapy has been remarkably effective across multiple cancer types, there continues to be a significant number of non-responding patients. A possible factor proposed to influence the efficacy of immunotherapies is the gut microbiome.
Daud, Adil, Humphries, Audrey
core +1 more source
Gut Microbiome and Gastrointestinal Diseases
The Korean Journal of Clinical Laboratory Science, 2018 본 연구에서는 최근에 연구되어 온 장내 세균총이 특히 주요 장질환의 발병에 있어서, 어떠한 역할을 하는지 보고된 여러 문헌들을 중심으로 연구 결과들을 요약 하였다. 예를 들자면, 면역체계를 매개하여 병이 악화되는 여러 질환에서 정상일 때와 달리 바뀐 장내 세균총을 통해 악화된다고 보고된 바 있다. 장내 세균총의 역할에 대해 많이 연구된 장질환 중에서, 많이 연구된 3 개의 질환은 과민성 장 증후군, 염증성 장질환, 대장암이다. 그러나, 사람의 장내에 존재하는 세균총은 몸에 이로우며, 비타민A 합성, 단사슬지방산의 생산, 담즙산 대사과정과 같은 장내 생리적 기능 매개를 통해 장내 항상성을 유지한다고 알려져 있다.
Sung-Hoon Kim +2 more
openaire +3 more sources
The Equine Gastrointestinal Microbiome: Impacts of Age and Obesity [PDF]
Frontiers in Microbiology, 2018 Gastrointestinal microbial communities are increasingly being implicated in host susceptibilities to nutritional/metabolic diseases; such conditions are more prevalent in obese and/or older horses. This controlled study evaluated associations between host-phenotype and the fecal microbiome / metabolome.
Dai Grove-White +8 more
openaire +3 more sources
Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]
, 2013 Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta +7 more
core +3 more sources
Effects of Toxic Fescue Exposure on Vaginal Microbial Communities of Crossbred Beef Cows [PDF]
, 2018 The consumption of toxic fescue by beef cattle results in several adverse physiological effects such as reduced reproductive success, severe vasoconstriction resulting in hoof sloughing, low body condition scores, hyperthermia, decreased prolactin levels,
Ratton, Abby
core +2 more sources
Dirichlet-tree multinomial mixtures for clustering microbiome compositions [PDF]
arXiv, 2020 Studying the human microbiome has gained substantial interest in recent years, and a common task in the analysis of these data is to cluster microbiome compositions into subtypes. This subdivision of samples into subgroups serves as an intermediary step in achieving personalized diagnosis and treatment. In applying existing clustering methods to modern
arxiv
MIMIX: a Bayesian Mixed-Effects Model for Microbiome Data from Designed Experiments [PDF]
arXiv, 2017 Recent advances in bioinformatics have made high-throughput microbiome data widely available, and new statistical tools are required to maximize the information gained from these data. For example, analysis of high-dimensional microbiome data from designed experiments remains an open area in microbiome research.
arxiv
Alterations to the Gastrointestinal Microbiome Associated with Methamphetamine Use among Young Men who have Sex with Men. [PDF]
, 2019 Methamphetamine (MA) use is a major public health problem in the United States, especially among people living with HIV (PLWH). Many MA-induced neurotoxic effects are mediated by inflammation and gut microbiota may play a role in this process, yet the ...
Aldrovandi, Grace M +11 more
core
Long-term impact of fecal transplantation in healthy volunteers [PDF]
, 2019 Fecal microbiota transplantation (FMT) has been recently approved by FDA for the treatment of refractory recurrent clostridial colitis (rCDI). Success of FTM in treatment of rCDI led to a number of studies investigating the effectiveness of its ...
Egozcue Rubí, Juan José +3 more
core +2 more sources