Results 81 to 90 of about 117,099 (295)

Microbiome–host-phylogeny relationships in animal gastrointestinal tract microbiomes

FEMS Microbiology Ecology, 2022
Abstract Among the factors influencing the animal gastrointestinal tract microbiome (AGM) diversity, diet and phylogeny have been extensively studied. However, what made the studies particularly challenging is that diet characteristics per se are product of evolution, and hence totally disentangling both effects is unrealistic, likely ...
Zhanshan (Sam) Ma, Wendy Li, Peng Shi
openaire   +2 more sources

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Gut Microbiota‐Derived 3‐Hydroxybutyrate Blocks GPR43‐Mediated IL6 Signaling to Ameliorate Radiation Proctopathy

Advanced Science
Radiation proctopathy (RP) is a common complication of radiotherapy for pelvic malignancies with high incidence. RP accompanies by microbial dysbiosis. However, how the gut microbiota affects the disease remains unclear.
Zhenhuang Ge, Chun Chen, Junyi Chen, Zhou Jiang, Lingming Chen, Yingqi Wei, Haiyang Chen, Lei He, Yi Zou, Xiaoxuan Long, Hongyu Zhan, Huaiming Wang, Hui Wang, Yongjun Lu   +13 more
doaj   +1 more source

STUDYING THE GASTROINTESTINAL MICROBIOME OF A TRADITIONAL PERUVIAN COMMUNITY [PDF]

, 2018
The human gastrointestinal (GI) tract is an ecosystem that is home to a plethora of bacteria, archaea, microeukaryotes, and viruses, collectively termed the “gut microbiota” or “microbiome” when referring to the genetic material of the microbiota.
Patel, Nisha
core  

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Gut Microbiota and Gastrointestinal Symptoms in the Global Assessment of Obsessive–Compulsive Disorder: A Narrative Review of Current Evidence and Practical Implications

Brain Sciences
A growing body of literature suggests a link between bowel syndromes (e.g., irritable bowel syndrome and inflammatory bowel disease), gut microbiome alterations, and psychiatric disorders.
Giacomo Grassi, Ilenia Pampaloni
doaj   +1 more source

Emerging trends and research foci in gastrointestinal microbiome

Journal of Translational Medicine, 2019
Background Gastrointestinal microbiome has drawn an increasing amount of attention over the past decades. There is emerging evidence that the gut flora plays a major role in the pathogenesis of certain diseases.
Xiaoquan Huang, Xiaowen Fan, Jun Ying, Shiyao Chen   +3 more
doaj   +1 more source

The gut microbiome and its potential role in the development and function of newborn calf gastrointestinal tract [PDF]

, 2015
A diverse microbial population colonizes the sterile mammalian gastrointestinal tract during and after the birth. There is increasing evidence that this complex microbiome plays a crucial role in the development of the mucosal immune system and ...
Guan, Leluo, Grebiel, Philip J., Malmuthuge, Nilusha   +2 more
core   +2 more sources

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source