Results 71 to 80 of about 161,284 (254)

Protective Microbiota: From Localized to Long-Reaching Co-Immunity [PDF]

, 2017
Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance ...
Abt, Abt, Algburi, Altenhoefer, Altier, Anderson, Annuk, Asahara, Ashburner, Ayabe, Ayres, Barr, Barton, Bassis, Bassler, Becattini, Belkaid, Belkaid, Belkaid, Belkaid, Benson, Benveniste, Berg, Bevins, Birchenough, Birchenough, Blackburn, Bocci, Bohnhoff, Botes, Bouskra, Brandl, Braniste, Brenchley, Brestoff, Britton, Bron, Brugiroux, Budden, Buddington, Buffie, Buffie, Cani, Cani, Carey, Cash, Castagliuolo, Catford, Cebra, Cerf-Bensussan, Chatzidaki-Livanis, Chen, Chow, Chudnovskiy, Clarke, Clarke, Clarke, Cogen, Cogen, Cogen, Cotar, Cremer, Crost, Danielsson, Davidson, Davis, de Agüero, de Sablet, de Steenhuijsen Piters, Delhaes, Denny, Deriu, Dickson, Dickson, Dickson, Dickson, Donaldson, Donnet-Hughes, Eberl, El-Solh, Everett, Fagundes, Fardini, Fine, Fransen, Frantz, Franzenburg, Freter, Freter, Freter, Freter, Freter, Fubara, Fukuda, Gabryszewski, Gallichan, Gallo, Ganal, Gantois, Gauguet, Geva-Zatorsky, Gill, Gorjifard, Gutzeit, Henao-Mejia, Hersoug, Hibbing, Hooper, Hooper, Hooper, Hsiao, Ichinohe, Irie, Ivanov, Ivanov, Iwase, Kamada, Khosravi, Kinnunen, Knoop, Koch, Kolling, Kommineni, Laurent, Lawley, Levine, Little, Mack, Macpherson, Macpherson, Macpherson, Macpherson, Majlessi, Mallon, Maltby, Man, Mantis, Martins, Masson, Mazmanian, Mazmanian, McAleer, McKenney, Medzhitov, Melo, Mishra, Molloy, Murall, Mushin, Nagy, Nikkari, Oldroyd, Olier, Palm, Pamer, Pang, Perry, Pfeiffer, Pontier-Bres, Pradeu, Pradeu, Pradeu, Pérez-Santiago, Qin, Ramanan, Rasmussen, Rea, Rea, Ripert, Rizzetto, Robinson, Rolfe, Roossinck, Round, Ruhe, Råberg, Salzman, Sambanthamoorthy, Samuelson, Santagati, Santagati, Sassone-Corsi, Sassone-Corsi, Savage, Schamberger, Schieber, Schneider, Schuijt, Sharma, Shi, Shin, Shokouhfard, Shu, Siegrist, Soares, Sommer, Spees, Stapleton, Stappenbeck, Stecher, Stecher, Stinson, Strugnell, Sutyak Noll, Tanaka, Theriot, Tillmann, Tomkovich, Tomás, Tuomola, Ubeda, Underhill, Vaishnava, Valdés-Varela, Valdés-Varela, Valle, Van de Perre, van der Waaij, Vandecandelaere, Venkataraman, Villarino, Virgin, Virgin, Walker, Walsham, Weaver, Weingarden, Wexler, Whiteson, Wikoff, Willis, Wootton, Wright, Wu, Xiang, Yilmaz, Zagato, Zeng, Zipperer   +238 more
core   +4 more sources

Host-Gut Microbiota Metabolic Interactions and Their Role in Precision Diagnosis and Treatment of Gastrointestinal Cancers

Pharmacological Research
The critical role of the gut microbiome in gastrointestinal cancers is becoming increasingly clear. Imbalances in the gut microbial community, referred to as dysbiosis, are linked to increased risks for various forms of gastrointestinal cancers ...
Chunhao Cao, Siran Yue, Aiping Lu, Chao Liang   +3 more
doaj   +1 more source

Lumen and mucosa-associated Lactobacillus rhamnosus from the intestinal tract of organ donors

Gut Microbiome, 2020
Knowledge of the intra-individual spatial and regional distribution of intestinal microbial populations is essential to understand gut host–microbial interactions.
Alan J. Marsh, Al-Mounawara A. Yaya, Sandy Ng, Kshipra Chandrashekhar, Jeff Roach, Scott T. Magness, M. Andrea Azcarate-Peril   +6 more
doaj   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Intra-species Genomic and Physiological Variability Impact Stress Resistance in Strains of Probiotic Potential

Frontiers in Microbiology, 2018
Large-scale microbiome studies have established that most of the diversity contained in the gastrointestinal tract is represented at the strain level; however, exhaustive genomic and physiological characterization of human isolates is still lacking. With
Jason W. Arnold, Joshua B. Simpson, Jeffrey Roach, Jakub Kwintkiewicz, M. Andrea Azcarate-Peril   +4 more
doaj   +1 more source

Noninvasive sampling of the small intestinal chyme for microbiome, metabolome and antimicrobial resistance genes in dogs, a proof of concept

Animal Microbiome, 2023
Background The gastrointestinal microbiome and metabolome vary greatly throughout the different segments of the gastrointestinal tract, however current knowledge of gastrointestinal microbiome and metabolome in health and disease is limited to fecal ...
Julie Menard, Sahar Bagheri, Sharanya Menon, Y. Tina Yu, Laura B. Goodman   +4 more
doaj   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Relating the metatranscriptome and metagenome of the human gut [PDF]

, 2014
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R., Chan, Andrew T., Ciulla, Dawn, Earl, Ashlee M., Franzosa, Eric A., Garrett, Wendy S., Gevers, Dirk, Giannoukos, Georgia, Huttenhower, Curtis, Izard, Jacques, Morgan, Xochitl C., Reyes, Joshua, Segata, Nicola, Waldron, Levi   +13 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source