Results 81 to 90 of about 770,027 (273)
Nutrients, 2019 Previous studies have reported that probiotics may improve clinical and inflammatory parameters in patients with obesity and metabolic syndrome (MetS).
C. Tenorio-Jiménez +13 more
semanticscholar +1 more source
Advanced Science, EarlyView.The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang +22 more
wiley +1 more source
Advanced Science, EarlyView.The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli +16 more
wiley +1 more source
OralAll forms of life on Earth are dependent on microbes. In vertebrates, the oral cavity and the gastrointestinal tract are colonized by large numbers of microorganisms, which includes species from many life forms: bacteria, fungi, archaea, and protozoa ...
Mahmoud M. Bakr +6 more
doaj +1 more source
Moderate Traumatic Brain Injury Alters the Gastrointestinal Microbiome in a Time-Dependent Manner.
Shock, 2019 The microbiome is defined as the collective genomes of the microbes (composed of bacteria, bacteriophage, fungi, protozoa and viruses) that colonize the human body, and alterations have been associated with a number of disease states.
Susannah E. Nicholson +11 more
semanticscholar +1 more source
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
Advanced Science, EarlyView.We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Weaning age influences the severity of gastrointestinal microbiome shifts in dairy calves
Scientific Reports, 2017 Ruminants microbial consortium is responsible for ruminal fermentation, a process which converts fibrous feeds unsuitable for human consumption into desirable dairy and meat products, begins to establish soon after birth.
S. Meale +7 more
semanticscholar +1 more source
Advanced Science, EarlyView.A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang +11 more
wiley +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Candida albicans gastrointestinal colonization resistance: a host-microbiome balancing act
Infection and ImmunityWhile Candida albicans is a common, commensal yeast colonizing 50%–60% of humans, it has the potential to expand in the gastrointestinal tract and enter the blood stream resulting in invasive candidiasis.
Derek J. Bays, Hannah P. Savage
doaj +1 more source