Results 21 to 30 of about 915,734 (298)

The excitatory effect of hydrogen sulfide on rat colonic muscle contraction and the underlying mechanism

Journal of Pharmacological Sciences, 2022
H2S is a well-known relaxant regulator in muscle contraction but little attention has been paid to its excitatory effect on colonic motility. To investigate the excitation of H2S on rat colonic contraction and the underlying mechanism, the muscle ...
Xiaojing Quan, Wei Chen, Bin Qin, Jinhai Wang, Hesheng Luo, Fei Dai   +5 more
doaj   +1 more source

Enteric nervous system: sensory transduction, neural circuits and gastrointestinal motility

Nature reviews: Gastroenterology & hepatology, 2020
The gastrointestinal tract is the only internal organ to have evolved with its own independent nervous system, known as the enteric nervous system (ENS).
N. Spencer, Hongzhen Hu
semanticscholar   +1 more source

CARM1 promotes gastric cancer progression by regulating TFE3 mediated autophagy enhancement through the cytoplasmic AMPK-mTOR and nuclear AMPK-CARM1-TFE3 signaling pathways

Cancer Cell International, 2022
Background The role of CARM1 in tumors is inconsistent. It acts as an oncogene in most cancers but it inhibits the progression of liver and pancreatic cancers.
Suzhen Yang, Jing Zhang, Di Chen, Jiayi Cao, Ying Zheng, Yuying Han, Yirong Jin, Shuhui Wang, Ting Wang, Lin Ma, Tingting Luo, Yan Wang, Wen Qin, Lei Dong   +13 more
doaj   +1 more source

Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility

International Journal of Molecular Sciences, 2020
Millions of patients worldwide suffer from gastrointestinal (GI) motility disorders such as gastroparesis. These disorders typically include debilitating symptoms, such as chronic nausea and vomiting. As no cures are currently available, clinical care is
D. Foong, Jerry Zhou, A. Zarrouk, Vincent Ho, Michael D. O’Connor   +4 more
semanticscholar   +1 more source

The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis

Mediators of Inflammation, 2021
Background. Gastrointestinal motility disorder is a common gastrointestinal disease, which seriously affects life quality. Traditional Chinese medicine (TCM) has been widely used as an alternative therapy for gastrointestinal motility disorder.
Xuan Guo, Yin Xu, Hua-liang Tan, Xiao-juan Wang, Lin Xiao   +4 more
doaj   +1 more source

Endoscopic management of gastrointestinal motility disorders – part 1: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Endoscopy, 2020
Main Recommendations ESGE recommends the use of a graded pneumatic dilation protocol in achalasia, starting with a 30-mm dilation and followed by a 35-mm dilation at a planned interval of 2 – 4 weeks, with a subsequent 40-mm dilation when there is ...
B. Weusten, M. Barret, A. Bredenoord, P. Familiari, Jan-Michel Gonzalez, J. V. van Hooft, S. Ishaq, V. Lorenzo-Zúñiga, H. Louis, S. van Meer, H. Neumann, D. Pohl, F. Prat, D. von Renteln, E. Savarino, R. Sweis, J. Tack, R. Tutuian, J. Martínek   +18 more
semanticscholar   +1 more source

β1/2 or M2/3 Receptors Are Required for Different Gastrointestinal Motility Responses Induced by Acupuncture at Heterotopic or Homotopic Acupoints. [PDF]

PLoS ONE, 2016
Acupuncture at homotopic acupoints or heterotopic acupoints is known to either inhibit or facilitate gastrointestinal motility, depending on the acupoint location.
Xinyan Gao, Yuxue Zhao, Yangshuai Su, Kun Liu, Xiaochun Yu, Changxiang Cui, Zhaokun Yang, Hong Shi, Xianghong Jing, Bing Zhu   +9 more
doaj   +1 more source

Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility

Frontiers in Immunology, 2020
Toll-like receptor 4 (TLR4) recognizes exogenous pathogen-associated molecular patterns (PAMPs) and endogenous danger-associated molecular patterns (DAMPs) and initiates the innate immune response.
Peng Zhang, Meirong Yang, Chunhua Chen, Liu Liu, Xinchuan Wei, Si Zeng   +5 more
semanticscholar   +1 more source

Anatomical and functional maturation of the mid-gestation human enteric nervous system

Nature Communications, 2023
Immature gastrointestinal motility impedes preterm infant survival. The enteric nervous system controls gastrointestinal motility, yet it is unknown when the human enteric nervous system matures enough to carry out vital functions.
Lori B. Dershowitz, Li Li, Anca M. Pasca, Julia A. Kaltschmidt   +3 more
doaj   +1 more source

The mechanisms of nerve injury caused by viral infection in the occurrence of gastrointestinal motility disorder-related diseases

Virology Journal, 2023
Gastrointestinal motility refers to the peristalsis and contractility of gastrointestinal muscles, including the force and frequency of gastrointestinal muscle contraction.
Yaqian Li, Qiuyu Chen, Liwei Wang, Xin Chen, Bangmao Wang, Weilong Zhong   +5 more
doaj   +1 more source