Results 71 to 80 of about 970,087 (354)

Targeting γ-aminobutyric acid pathways in irritable bowel syndrome: bridging central nervous system, enteric dysfunction, and the microbiota-gut-brain axis

Frontiers in Pharmacology
Irritable bowel syndrome (IBS) is a complex and multifaceted disorder of the gut-brain interaction. Recent evidence suggests that γ-aminobutyric acid (GABA) may be involved in the development of IBS symptoms.
Christian Lambiase, Christian Lambiase, Francesco Rettura, Francesco Rettura, Francesco Rettura, Giusi Desirè Sciumè, Giusi Desirè Sciumè, Riccardo Tedeschi, Riccardo Tedeschi, Antonio Grosso, Antonio Grosso, Lorenzo Cancelli, Lorenzo Cancelli, Andrea Bottari, Andrea Bottari, Matteo Fornai, Luca Antonioli, Nicola de Bortoli, Nicola de Bortoli, Massimo Bellini, Massimo Bellini   +20 more
doaj   +1 more source

Diclofenac and dexamethasone modulate the effect of cannabidiol on the rat colon motility ex vivo

Journal of Veterinary Research, 2023
Due to the growing interest in the use of cannabinoids in supportive therapies, they are increasingly used together with anti-inflammatory drugs. Cannabinoids inhibit gastrointestinal motility, while steroidal and nonsteroidal anti-inflammatory drugs ...
Chłopecka Magdalena, Kiraga Łukasz, Crowley Kijan, Jank Michał, Latek Urszula, Mendel Marta, Karlik Wojciech   +6 more
doaj   +1 more source

Benefits of thoracic epidural analgesia in patients undergoing an open posterior component separation for abdominal herniorrhaphy [PDF]

, 2017
INTRODUCTION: The implementation of open posterior component separation (PCS) surgery has led to improved outcomes for complex hernias. While the PCS technique has been shown to decrease recurrence rates, and provide a feasible option to repair hernias ...
Sellers, Austin
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Quantitative gastrointestinal function and corresponding symptom profiles in autonomic neuropathy

Frontiers in Neurology, 2022
PurposePeripheral neuropathies with autonomic nervous system involvement are a recognized cause of gastrointestinal dysmotility for a wide spectrum of diseases.
Jordan S. Langford, Eric Tokita, Cecilia Martindale, Leah Millsap, James Hemp, Laura A. Pace, Melissa M. Cortez   +6 more
doaj   +1 more source

The survey of the effect of ginger extract on gastric residual volume in mechanically ventilated patients hospitalized in the Intensive Care Units [PDF]

, 2013
Background and purpose: Delayed gastric emptying in mechanically ventilated patients is common. According to evidences, Ginger can accelerate gastric emptying.
Ali Vakili, M., Amin, G., Eshghi Nia, S., Ghochae, A., Hekmat Fshar, M., Jouybari, L., Sanagoo, A.   +6 more
core  

Non-specific abdominal pain and air pollution: a novel association. [PDF]

, 2012
We studied whether short-term exposure to air pollution was associated with non-specific abdominal pain in epidemiologic and animal studies. Patients visiting the emergency department with non-specific abdominal pain were identified in Edmonton (1992 to
Fichna, Jakub, Ghosh, Subrata, Kaplan, Gilaad G., Madsen, Karen, Porada, Eugeniusz, Rowe, Brian H., Storr, Martin, Szyszkowicz, Mieczyslaw, Vincent, Renaud   +8 more
core   +3 more sources

Cholinergic activation of enteric glia is a physiological mechanism that contributes to the regulation of gastrointestinal motility.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2018
The reflexive activities of the gastrointestinal tract are regulated, in part, by precise interactions between neurons and glia in the enteric nervous system (ENS).
Ninotchska M Delvalle, D. Fried, Gretchen Rivera‐Lopez, Lukas Gaudette, Brian D. Gulbransen   +4 more
semanticscholar   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants.

PLoS ONE, 2020
ObjectiveThe gastrointestinal environment in which drug products need to disintegrate before the drug can dissolve and be absorbed has not been studied in detail due to limitations, especially invasiveness of existing techniques.
Khaled Heissam, Nichola Abrehart, Caroline L Hoad, Jeff Wright, Alex Menys, Kathryn Murray, Paul M Glover, Geoffrey Hebbard, Penny A Gowland, Jason Baker, William L Hasler, Robin C Spiller, Maura Corsetti, James G Brasseur, Bart Hens, Kerby Shedden, Joseph Dickens, Deanna M Mudie, Greg E Amidon, Gordon L Amidon, Luca Marciani   +20 more
doaj   +1 more source