Results 271 to 280 of about 1,620,741 (300)
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Pediatric Gastrointestinal Stromal Tumors
Hematology/Oncology Clinics of North America, 2009Gastrointestinal stromal tumors (GISTs) rarely occur in pediatric patients, but increased recognition of adult GIST has led to better awareness of the existence of this entity in the pediatric population. GIST occurring in pediatric patients has a unique biology and clinical behavior and warrants discussion as an independent entity.
Alberto S, Pappo, Katherine A, Janeway
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Management of Gastrointestinal Stromal Tumors
Surgical Clinics of North America, 2017Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm of the gastrointestinal tract. The stomach is the most common site of origin. Management of GISTs changed after the introduction of molecularly targeted therapies. Although the only potentially curative treatment of resectable primary GISTs is surgery, recurrence is common.
Emily Z, Keung, Chandrajit P, Raut
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Management of Gastrointestinal Stromal Tumors
Surgical Clinics of North America, 2016Gastrointestinal stromal tumors had the reputation for poor outcomes because of their lack of response to nonsurgical interventions. The discovery of gain-of-function mutations involving receptor tyrosine kinase growth factor receptors altered the biological understanding and management.
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Gastrointestinal stromal tumors and leiomyosarcomas
Journal of Surgical Oncology, 2008AbstractOnly recently has gastrointestinal stromal tumor (GIST) been recognized as the most frequent GI mesenchymal neoplasm. Prior to the use of KIT staining, most GI stromal tumors were identified as leiomyosarcoma (LMS). For primary GIST, surgery remains the principal treatment and adjuvant imatinib may improve outcomes.
Steven C, Katz, Ronald P, DeMatteo
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Pediatric Gastrointestinal Stromal Tumor
Journal of Pediatric Gastroenterology and Nutrition, 2023Łukasz Dembiński +3 more
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Colorectal gastrointestinal stromal tumor
Techniques in Coloproctology, 2010Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm arising in the digestive tract, with an estimated prevalence of 15-20 per 1,000,000. GISTs are related to the interstitial cells of Cajal and are characterized by constitutive over-expression of the transmembrane tyrosine kinase receptor KIT.
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Molecular Pathogenesis of Gastrointestinal Stromal Tumor: A Paradigm for Personalized Medicine
Annual Review of Pathology: Mechanisms of Disease, 2022Brian P. Rubin, Josephine K Dermawan
exaly
Gastrointestinal Stromal Tumor
Journal of Pediatric Gastroenterology and Nutrition, 2006David L, Suskind +2 more
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Gastrointestinal stromal tumors
DMW - Deutsche Medizinische Wochenschrift, 2003M, Schlemmer +4 more
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