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Gastrointestinal Stromal Tumors
Current Oncology ReportsThis review aims to outline the current understanding of the molecular drivers and treatment paradigms of gastrointestinal stromal tumors, with a focus on recent developments in treatment in the advanced disease setting.There have been recent advancements in our understanding of the molecular biology of gastrointestinal stromal tumors, including the ...
Helbing A, Menon G.
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Gastrointestinal Stromal Tumors [PDF]
Journal of Clinical Oncology, 2018 GI stromal tumors (GISTs) are neoplasms with a varying malignancy potential ranging from virtually indolent tumors to rapidly progressing cancers. GISTs occur throughout the intestinal tract, and most harbor an activating mutation in either KIT or platelet-derived growth factor A ( PDGFRA).
Margaret, von Mehren, Heikki, Joensuu
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[Gastrointestinal stromal tumors]. [PDF]
Annali italiani di chirurgia, 2011 Gastrointestinal stromal tumor (GIST) account for 1% of all gastrointestinal neoplasms and are the most common mesenchymal tumor of gastrointestinal tract. There are considered to originate fom the intestinal cell of Cajal, an intestinal pacemaker cell, characterized usually express the KIT protein on immunohistochemistry.
Ridolfini, Mp +7 more
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Gastrointestinal Stromal Tumors [PDF]
Cancer Control, 2001 Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. A relationship to the interstitial cells of Cajal (ICCs) has been proposed, and expression of CD117, the c-kit receptor present in ICCs, has been suggested as a marker for GISTs.The English literature has been reviewed with an emphasis on ...
L, Strickland +2 more
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Gastrointestinal stromal tumor [PDF]
World Journal of Surgical Oncology, 2009 GISTs are a subset of mesenchymal tumors and represent the most common mesenchymal neoplasms of GI tract. However, GIST is a recently recognized tumor entity and the literature on these stromal tumors has rapidly expanded.An extensive review of the literature was carried out in both online medical journals and through Athens University Medical library.
Stamatakos, M. +6 more
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Gastrointestinal Stromal Tumors [PDF]
Gastroenterology Clinics of North America, 2013 Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of the gastrointestinal tract. Soon after GIST was recognized as a tumor driven by a KIT or platelet-derived growth factor receptor mutation, it became the first solid tumor target for tyrosine kinase inhibitor therapies.
Markku, Miettinen, Jerzy, Lasota
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Rectal Gastrointestinal Stromal Tumors
Cureus, 2023 Rectal gastrointestinal stromal tumors (GISTs) are rare types of tumors, but the incidence is increasing, and we now know more about the pathogenesis and management of rectal GIST. The main goal is to resect the tumor with negative microscopic margins. With the development of neoadjuvant Imatinib therapy, preoperative reduction in tumor size has become
Dawara, Shahed A +2 more
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A narrative review of imatinib-resistant gastrointestinal stromal tumors [PDF]
, 2021 Yujiro Hayashi, Vy Truong Thuy Nguyen
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Gastrointestinal stromal tumor (GIST)
Current Treatment Options in Gastroenterology, 2006 Gastrointestinal stromal tumors (GISTs), the most common nonepithelial neoplasms of the gastrointestinal (GI) tract, occur most commonly in the stomach. These neoplasms were previously classified as smooth muscle tumors, but it has become apparent that they represent distinct clinicopathologic entities.
Mitchell L, Schubert, Robert, Moghimi
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Imaging Gastrointestinal Stromal Tumors
Cancer Control, 2005 Background: Because of the recent reclassification of mesenchymal tumors, which was based on a better understanding of the genetics and immunophenotype of gastrointestinal stromal tumors (GISTs), only a limited number of studies have described the radiologic appearance of GISTs.
Marla R, Hersh +3 more
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