Results 21 to 30 of about 54,012 (256)

Gastrointestinal Stromal Tumors with Unusual Presentations: Case Series [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2012
Background: Gastrointestinal stromal tumors are rare mesenchymal tumors; and it may be presented by a variety of manifestations.. Case Presentation: A 56-year-old Egyptian male patient presented with a massive gastrointestinal bleeding with hemodynamic ...
Magdy El-Moghazy, Tarik Ezzat, Tarik Zaher, Mohamed Emara, Mohamed Refaey   +4 more
doaj   +1 more source

Neuroendocrine Tumor with Metachronous Gastrointestinal Stromal Tumor in a Patient: A Case Report

The Korean Journal of Gastroenterology, 2022
Neuroendocrine tumors (NETs) that arise from neuroendocrine cells can develop in most organs; however, it is rarely found in the duodenal papilla.
Jae Hyuk Heo, Eun Jeong Choi, Seung Jung Yu, Yo Han Park, Jung Sik Choi   +4 more
doaj   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Pathology of Gastrointestinal Stromal Tumors

Clinical Medicine Insights: Pathology, 2012
Gastrointestinal stromal tumor (GIST) is a well recognized and relatively well understood soft tissue tumor. Early events in GIST development are activating mutations in KIT or PDGFRA , which occur in most GISTs and encode for mutated tyrosine receptor ...
Wai Chin Foo, Bernadette Liegl-Atzwanger, Alexander J. Lazar   +2 more
doaj   +2 more sources

Laparoscopic treatment of gastrointestinal stromal tumors located at the duodenojejunal junction

SAGE Open Medical Case Reports, 2020
Gastrointestinal stromal tumors are the most common subepithelial tumors of the gastrointestinal tract. Gastrointestinal stromal tumors are commonly detected in the stomach followed by the small intestine.
Seokyoun Lee, Jungnam Kwon, Junhee Lee
doaj   +1 more source

New Risk Classification of Gastrointestinal Stromal Tumors Based on Tumor Size and Three Indices Derived from Rapid Flow Cytometry of Fine-Needle Aspiration Specimens

Tokyo Women's Medical University Journal, 2023
Background: Biopsies of suspected gastrointestinal stromal tumors in submucosal locations, which were once a challenge, are now easily performed with endoscopic ultrasound-guided fine-needle aspiration.
Kiyoaki Taniguchi, Akane Suzuki, Akiko Serizawa, Sho Kotake, Shunichi Ito, Kazuomi Suzuki, Sho Izumika, Masaho Ota, Yoshihiro Muragaki, Masakazu Yamamoto   +9 more
doaj   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

En bloc corpectomy for late gastrointestinal stromal tumor metastasis: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background Spinal metastases of gastrointestinal stromal tumors are rare; however, the incidence has been increasing since the introduction of tyrosine kinase inhibitors, which have improved overall survival.
Takaki Shimizu, Hideki Murakami, Apiruk Sangsin, Satoru Demura, Satoshi Kato, Kazuya Shinmura, Noriaki Yokogawa, Norihiro Oku, Ryo Kitagawa, Hiroyuki Tsuchiya   +9 more
doaj   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source