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Pediatric gastrointestinal stromal tumor
Seminars in Pediatric Surgery, 2012Pediatric gastrointestinal stromal tumor (GIST) is a rare entity that can be quite different from its adult counterpart. This report provides a comprehensive review on the diagnosis and management of this tumor in children and adolescents, including its oncogenesis and associated syndromes.
Katherine A, Janeway +1 more
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Pediatric Gastrointestinal Stromal Tumors
Hematology/Oncology Clinics of North America, 2009Gastrointestinal stromal tumors (GISTs) rarely occur in pediatric patients, but increased recognition of adult GIST has led to better awareness of the existence of this entity in the pediatric population. GIST occurring in pediatric patients has a unique biology and clinical behavior and warrants discussion as an independent entity.
Alberto S, Pappo, Katherine A, Janeway
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Gastrointestinal stromal tumors (GISTs)
Current Opinion in Gastroenterology, 2004Gastrointestinal stromal tumors (GISTs) have recently been the subject of considerable clinical and experimental interest. This focus is based on the recognition that GISTs characteristically have uncontrolled activation of the KIT protein, a transmembrane tyrosine kinase receptor involved in cell survival, development, and proliferation.
Mandeep S, Saund +2 more
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Gastrointestinal stromal tumors
Current Treatment Options in Oncology, 2000The nonepithelial, nonlymphoid tumors of the gastrointestinal tract are heterogeneous in terms of clinical presentation, behavior, pathology, and genetic features. Concepts regarding these tumors have changed rapidly over the past decade as nomenclature has evolved. Many of these tumors have no muscle differentiation, and designations such as leiomyoma
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Gastrointestinal Stromal Tumors
American Journal of Therapeutics, 2016The understanding of aberrant molecular pathways that result in gastrointestinal stromal tumors (GISTs) and the rapid development of molecular therapies that target these pathways represent one of the great milestones in translational oncology.
Aakanksha Prasad, Asija +3 more
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Colorectal gastrointestinal stromal tumor
Techniques in Coloproctology, 2010Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm arising in the digestive tract, with an estimated prevalence of 15-20 per 1,000,000. GISTs are related to the interstitial cells of Cajal and are characterized by constitutive over-expression of the transmembrane tyrosine kinase receptor KIT.
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Pediatric Gastrointestinal Stromal Tumor
Journal of Pediatric Gastroenterology and Nutrition, 2023Łukasz, Dembiński +3 more
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Gastrointestinal Stromal Tumor
Journal of Pediatric Gastroenterology and Nutrition, 2006David L, Suskind +2 more
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