Results 21 to 30 of about 21,132 (237)

Review article: An analysis of the pharmacological rationale for selecting drugs to inhibit vomiting or increase gastric emptying during treatment of gastroparesis

open access: yesAlimentary Pharmacology and Therapeutics, 2023
Drugs which can inhibit nausea/vomiting and/or increase gastric emptying are used to treat gastroparesis, mostly ‘off‐label’. Within each category, they act at different targets and modulate different physiological mechanisms.
G. Sanger, P. Andrews
semanticscholar   +1 more source

Targeting the pylorus in gastroparesis: From physiology to endoscopic pyloromyotomy

open access: yesNeurogastroenterology and Motility, 2023
The pylorus plays a key role in the control of gastric content outflow. Impairment of pyloric physiology has been observed in gastroparesis, particularly when associated with diabetes mellitus or opioid intake or after antireflux surgery.
Heithem Soliman, G. Gourcerol
semanticscholar   +1 more source

Gastric electrical stimulation versus per‐oral pyloromyotomy for the treatment of nausea and vomiting associated with gastroparesis: An observational study of two cohorts

open access: yesNeurogastroenterology and Motility, 2023
Both gastric electrical stimulation (GES) and gastric‐peroral endoscopic myotomy (G‐POEM) can be offered to patients with gastroparesis and predominant nausea and vomiting.
G. Gourcerol   +12 more
semanticscholar   +1 more source

Buspirone for early satiety and symptoms of gastroparesis: A multi‐centre, randomised, placebo‐controlled, double‐masked trial (BESST)

open access: yesAlimentary Pharmacology and Therapeutics, 2023
Patients with gastroparesis and related disorders have symptoms including early satiety, postprandial fullness and bloating. Buspirone, a 5‐HT1 receptor agonist, may improve fundic accommodation.
H. Parkman   +17 more
semanticscholar   +1 more source

Gastroparesis [PDF]

open access: yesClinical Gastroenterology and Hepatology, 2019
A reader raises questions about diabetic gastroparesis (April 2019).
Mostafa Elfeky   +2 more
semanticscholar   +4 more sources

Epidemiology, etiology and treatment of gastroparesis: real-world evidence from a large US national claims database.

open access: yesGastroenterology, 2021
BACKGROUND & AIMS While gastroparesis carries a considerable healthcare and patient burden, associated epidemiological data are limited. To provide new real-world evidence for gastroparesis, we estimated disease prevalence, and investigated patient ...
Y. Ye   +5 more
semanticscholar   +1 more source

Prevalence of delayed gastric emptying in patients with gastroparesis‐like symptoms

open access: yesAlimentary Pharmacology and Therapeutics, 2023
The European consensus defined gastroparesis as a condition characterised by delayed gastric emptying (GE) in the absence of mechanical obstruction, with a symptom pattern of predominant nausea and/or vomiting and overlapping postprandial distress ...
I. Huang   +8 more
semanticscholar   +1 more source

Imaging in Gastroparesis: Exploring Innovative Diagnostic Approaches, Symptoms, and Treatment

open access: yesLife, 2023
Gastroparesis (GP) is a chronic disease characterized by upper gastrointestinal symptoms, primarily nausea and vomiting, and delayed gastric emptying (GE), in the absence of mechanical GI obstruction. The underlying pathophysiology of GP remains unclear,
F. Mandarino   +7 more
semanticscholar   +1 more source

Gastrointestinal-Specific symptom anxiety in patients with gastroparesis: Relationships to symptom severity and quality of life

open access: yesNeurogastroenterology and Motility, 2023
Gastrointestinal (GI)‐specific anxiety has been identified as a treatment target in irritable bowel syndrome. However, GI‐specific anxiety has been understudied in other GI functional/motility disorders.
Samuel E Tanner   +4 more
semanticscholar   +1 more source

Computational modeling of drug dissolution in the human stomach: Effects of posture and gastroparesis on drug bioavailability. [PDF]

open access: yesThe Physics of Fluids, 2022
The oral route is the most common choice for drug administration because of several advantages, such as convenience, low cost, and high patient compliance, and the demand and investment in research and development for oral drugs continue to grow.
Jae Ho Lee   +4 more
semanticscholar   +1 more source

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