Results 161 to 170 of about 2,582 (208)

Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling. [PDF]

open access: yesProc Natl Acad Sci U S A
Ota N   +24 more
europepmc   +1 more source

S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers. [PDF]

open access: yesPharmaceuticals (Basel)
Ananian AA   +11 more
europepmc   +1 more source
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Mechanisms of Gastroprotection

Scandinavian Journal of Gastroenterology, 1990
Gastric mucosa is constantly exposed to various irritants, but it usually maintains its integrity owing to several lines of defense, including mucus-alkaline secretion, mucosal hydrophobicity, rich mucosal blood flow, stabilization of tissue lysosomes, maintenance of mucosal sulfhydryls, and rapid proliferation and renewal of mucosal cells ...
exaly   +3 more sources

Gastroprotective Therapy

Veterinary Clinics of North America: Small Animal Practice, 2021
A range of gastroprotective drugs are available for the treatment of esophagitis and gastroduodenal mucosal injury including acid suppressants (ie, histamine-2 receptor antagonists, proton pump inhibitors), coating agents, prostaglandin analogs, and antacids. Of these, the proton pump inhibitors are the most effective drugs for the medical treatment of
openaire   +2 more sources

Effect of menthol in experimentally induced ulcers: Pathways of gastroprotection [PDF]

open access: yesChemico-Biological Interactions, 2013
Based on ethnopharmacological indications that Mentha species may be used in the treatment of gastrointestinal diseases, this study aimed to characterize the gastroprotective mechanisms of menthol (ME), the major compound of the essential oil from ...
Ariane L. Rozza   +2 more
exaly   +2 more sources

Gastroprotective and Antisecretory Effects of Ebrotidine

Scandinavian Journal of Gastroenterology, 1992
This study was designed to assess the gastroprotective and secretory effects of ebrotidine, a novel H2-receptor antagonist, in humans. Two groups (A and B) of male subjects with normal gastric mucosa were used. Group A (six subjects) was treated for 3 days with either ebrotidine or placebo in a randomized, crossover study, and on the 4th day 100 ml of ...
S J, Konturek   +5 more
openaire   +2 more sources

Gastroprotection in neurosurgery: the practice in Great Britain

British Journal of Neurosurgery, 1997
The indications for gastroprotection concurrent with corticosteroid use or as prophylaxis for stress ulceration in the neurosurgical intensive care unit remain unclear. The purpose of this study was to determine to what extent gastroprotection is practised in neurosurgical units in the British Isles.
T A Carroll, D Rawluk
exaly   +3 more sources

Thymoquinone: Novel gastroprotective mechanisms

European Journal of Pharmacology, 2012
Ample of evidence proved the gastroprotective effect of thymoquinone (TQ), the main constituent of Nigella sativa oil; however, the full mechanistic cassette on the gastric ulcer etiopathogenesis is not fully elucidated. The aim of the present work is to unveil some of the possible mechanisms.
Mahmoud-Awny, Magdy   +2 more
openaire   +2 more sources

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