Case Report: Treatment of refractory lung disease in systemic juvenile idiopathic arthritis with cyclophosphamide and rituximab combination therapy. [PDF]
Freeman WJ, Rife EC, Cron RQ.
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Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling. [PDF]
Ota N +24 more
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Cheonggukjang-Derived <i>Bacillus</i> Strains Exhibit Protective Effects Against HCl/Ethanol-Induced Gastric Injury Associated with Reduced Inflammatory Responses. [PDF]
Lee YS, Kim S.
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S-Methylmethionine (Vitamin U): A Critical Narrative Review of Pharmacological Mechanisms, Evidence Levels, and Translational Barriers. [PDF]
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Mechanisms of Gastroprotection
Scandinavian Journal of Gastroenterology, 1990Gastric mucosa is constantly exposed to various irritants, but it usually maintains its integrity owing to several lines of defense, including mucus-alkaline secretion, mucosal hydrophobicity, rich mucosal blood flow, stabilization of tissue lysosomes, maintenance of mucosal sulfhydryls, and rapid proliferation and renewal of mucosal cells ...
exaly +3 more sources
A range of gastroprotective drugs are available for the treatment of esophagitis and gastroduodenal mucosal injury including acid suppressants (ie, histamine-2 receptor antagonists, proton pump inhibitors), coating agents, prostaglandin analogs, and antacids. Of these, the proton pump inhibitors are the most effective drugs for the medical treatment of
openaire +2 more sources
Effect of menthol in experimentally induced ulcers: Pathways of gastroprotection [PDF]
Based on ethnopharmacological indications that Mentha species may be used in the treatment of gastrointestinal diseases, this study aimed to characterize the gastroprotective mechanisms of menthol (ME), the major compound of the essential oil from ...
Ariane L. Rozza +2 more
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Gastroprotective and Antisecretory Effects of Ebrotidine
Scandinavian Journal of Gastroenterology, 1992This study was designed to assess the gastroprotective and secretory effects of ebrotidine, a novel H2-receptor antagonist, in humans. Two groups (A and B) of male subjects with normal gastric mucosa were used. Group A (six subjects) was treated for 3 days with either ebrotidine or placebo in a randomized, crossover study, and on the 4th day 100 ml of ...
S J, Konturek +5 more
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Gastroprotection in neurosurgery: the practice in Great Britain
British Journal of Neurosurgery, 1997The indications for gastroprotection concurrent with corticosteroid use or as prophylaxis for stress ulceration in the neurosurgical intensive care unit remain unclear. The purpose of this study was to determine to what extent gastroprotection is practised in neurosurgical units in the British Isles.
T A Carroll, D Rawluk
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Thymoquinone: Novel gastroprotective mechanisms
European Journal of Pharmacology, 2012Ample of evidence proved the gastroprotective effect of thymoquinone (TQ), the main constituent of Nigella sativa oil; however, the full mechanistic cassette on the gastric ulcer etiopathogenesis is not fully elucidated. The aim of the present work is to unveil some of the possible mechanisms.
Mahmoud-Awny, Magdy +2 more
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