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Aqueous extract of the bark of Uncaria tomentosa, an amazonian medicinal plant, promotes gastroprotection and accelerates gastric healing in rats.

Journal of Ethnopharmacology, 2023
ETHNOPHARMACOLOGICAL IMPORTANCE Uncaria tomentosa Willd. DC., is used in the Amazonian region of South America, wherein ethnic groups use the plant to treat diseases, including gastric disorders.
Viviane L. Simomura   +13 more
semanticscholar   +1 more source

Interaction of Corticotropin-Releasing Factor and Capsaicin-Sensitive Afferent Neurons in Gastroprotection

Успехи физиологических наук, 2023
—Corticotropin-releasing factor (CRF) and capsaicin-sensitive afferent neurons with efferent-like function (CSN) make an important contribution to the regulation of the functions of the gastrointestinal tract (GIT) and gastroprotection.
N. Yarushkina   +3 more
semanticscholar   +1 more source

Gastroprotective Therapy

Veterinary Clinics of North America: Small Animal Practice, 2021
A range of gastroprotective drugs are available for the treatment of esophagitis and gastroduodenal mucosal injury including acid suppressants (ie, histamine-2 receptor antagonists, proton pump inhibitors), coating agents, prostaglandin analogs, and antacids. Of these, the proton pump inhibitors are the most effective drugs for the medical treatment of
openaire   +2 more sources

Alpha‐lipoic acid: A promising adjuvant for nonsteroidal anti‐inflammatory drugs therapy with improved efficacy and gastroprotection

Drug development research (Print), 2021
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly used in a wide variety of diseases due to their analgesic and anti‐inflammatory effects, but their usage have been limited due to significant ulcerogenic side effects.
Elif Nur Barut   +5 more
semanticscholar   +1 more source

Thymoquinone: Novel gastroprotective mechanisms

European Journal of Pharmacology, 2012
Ample of evidence proved the gastroprotective effect of thymoquinone (TQ), the main constituent of Nigella sativa oil; however, the full mechanistic cassette on the gastric ulcer etiopathogenesis is not fully elucidated. The aim of the present work is to unveil some of the possible mechanisms.
Mahmoud-Awny, Magdy   +2 more
openaire   +2 more sources

Research on the structural characteristics of a novel Chinese Iron Yam polysaccharide and its gastroprotection mechanism against ethanol-induced gastric mucosal lesion in a BALB/c mouse model.

Food & Function, 2020
In this study, a triple-helix Chinese Iron Yam polysaccharide (CIYP) with a molecular weight of 1.67 × 103 kDa was obtained. The CIYP was extracted with deionized water followed by deproteination, decoloration and purification using anion-exchange ...
Mingzhu Guo   +3 more
semanticscholar   +1 more source

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