In vitro expression of the goose astrovirus Cap protein delivered with a duck enteritis virus vector [PDF]
Background Goose astrovirus (GAstV) is an emerging pathogen that is widely distributed throughout China and can cause visceral gout, resulting in serious economic losses for the goose industry.
Liu Chen +7 more
doaj +2 more sources
Molecular characterization of a virulent goose astrovirus genotype-2 with high mortality in vitro and in vivo [PDF]
: Goose astrovirus (GAstV) is a newly identified viral pathogen threatening waterfowl, exhibiting a high prevalence across various regions in China. Notably, the Guanghan District of Deyang City, situated in Sichuan Province, has faced a outbreak of ...
Linhua Xu +17 more
doaj +2 more sources
Aminoguanidine alleviates gout in goslings experimentally infected with goose astrovirus-2 by reducing kidney lesions [PDF]
: Goose astrovirus (GAstV)-2, a novel pathogen identified in 2018, mainly causes visceral gout in goslings, leading to approximately 50% mortality. At present, no commercial veterinary products are available to prevent and treat the disease. Our previous
Ming Zhu +6 more
doaj +2 more sources
Viperin suppresses goose astrovirus type 2 replication through inhibition of viral RdRP activity. [PDF]
Goose astrovirus 2 (GAstV-2) infection induces visceral gout in goslings, resulting in high mortality rates in birds aged 3–15 days. Despite extensive research since the virus was first identified in 2018, the innate immune defense mechanisms of the host
Xu H +5 more
europepmc +2 more sources
Splenic transcriptomic profiling reveals innate immune responses and RIG-I-like receptor signaling in goslings infected with goose astrovirus. [PDF]
Goose astrovirus (GAstV) is an important pathogen associated with visceral gout, growth retardation, and mortality in goslings, whereas the splenic response to infection remains poorly understood.
Peng G +8 more
europepmc +2 more sources
Isolation and characterization of a goose astrovirus 1 strain causing fatal gout in goslings, China
: In recent years, goose gout, a severe infectious disease, has affected the development of the goose industry in China. Two different genotypes of goose astrovirus (GAstV), named as GAstV-1 and GAstV-2, were identified.
A.P. Wang +9 more
doaj +1 more source
Integrative transcriptomics and proteomics analysis provide a deep insight into goose astrovirus-host interactions during GAstV infection. [PDF]
: Goose astrovirus (GAstV) is a newly discovered astrovirus. GAstV causes gout and death in 4- to -16-day-old goslings. For the past few years, fatal gout, the cardinal clinical symptom of gosling infected with GAstV, has been spreading rapidly in some ...
Shi J +6 more
europepmc +2 more sources
Rapid extraction-free RT-RAA assay for on-site detection of goose astrovirus type 1 in goslings. [PDF]
Goose astrovirus type 1 (GAstV-1) is a major pathogen threatening the goose industry in China, frequently causing severe digestive tract lesions and growth retardation in goslings.
Yang Z +14 more
europepmc +2 more sources
AGXT-Driven Bile Acid Dysregulation Triggers Viral Gout in Astrovirus-Infected Jiangnan White Geese. [PDF]
Goose astrovirus (GAstV) infection has emerged as a prevalent cause of urate deposition and viral gout in major goose farming across China, leading to high mortality and substantial economic losses. However, the molecular mechanisms linking GAstV to gout
Fan S +9 more
europepmc +2 more sources
Isolation, Characterization, and Comparative Analysis of Two Subtypes of Goose Astrovirus in Guangdong Province, China. [PDF]
Since 2017, an infectious disease characterized by gosling gout and caused by goose astrovirus (GAstV) has affected geese in most major goose-producing regions of China.
Liu C +10 more
europepmc +2 more sources

